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PTP4A1 antibody (C-Term)

PTP4A1 Reactivity: Human, Mouse, Rat, Dog WB, EIA Host: Goat Polyclonal unconjugated
Catalog No. ABIN374988
  • Target See all PTP4A1 Antibodies
    PTP4A1 (Protein Tyrosine Phosphatase Type IVA, Member 1 (PTP4A1))
    Binding Specificity
    • 11
    • 9
    • 8
    • 6
    • 3
    C-Term
    Reactivity
    Human, Mouse, Rat, Dog
    Host
    • 42
    • 2
    • 1
    Goat
    Clonality
    • 45
    Polyclonal
    Conjugate
    • 15
    • 6
    • 6
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PTP4A1 antibody is un-conjugated
    Application
    • 26
    • 24
    • 8
    • 5
    • 5
    • 4
    • 3
    • 2
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Sequence
    KDSNGHRNNC CIQ
    Specificity
    This antibody reacts to PTP4A1 / PRL-1.
    Cross-Reactivity (Details)
    Species reactivity (expected):Mouse, Rat, Canine (Dog).
    Species reactivity (tested):Human.
    Purification
    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
    Immunogen
    Peptide with sequence from the C Terminus of the protein sequence (NP_003454.1). Genename: PTP4A1
    Top Product
    Discover our top product PTP4A1 Primary Antibody
  • Application Notes
    Peptide ELISA: 1/2000. Western Blot: 1 - 3 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    PTP4A1 (Protein Tyrosine Phosphatase Type IVA, Member 1 (PTP4A1))
    Alternative Name
    PTP4A1 / PRL1 (PTP4A1 Products)
    Synonyms
    ptp4a1 antibody, MGC83351 antibody, hh72 antibody, prl1 antibody, prl-1 antibody, MGC79517 antibody, ptpcaax1 antibody, ptp(caax1) antibody, fb54d08 antibody, fc01c04 antibody, wu:fb54d08 antibody, wu:fc01c04 antibody, zgc:101726 antibody, Ptp4a1 antibody, PRL-1 antibody, PTP4A1 antibody, PRL1 antibody, DKFZp459E022 antibody, AA415290 antibody, AU019864 antibody, C130021B01 antibody, Prl-1 antibody, HH72 antibody, PTP(CAAX1) antibody, PTPCAAX1 antibody, protein tyrosine phosphatase type IVA, member 1 antibody, protein tyrosine phosphatase type IVA, member 1 L homeolog antibody, protein tyrosine phosphatase 4a1 antibody, PTP4A1 antibody, ptp4a1.L antibody, ptp4a1 antibody, Ptp4a1 antibody
    Background
    The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs), which contains a PTP domain and a characteristic C-terminal prenylation motif. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This tyrosine phosphatase is a nuclear protein, but may primarily associate with plasma membrane. The surface membrane association of this protein depends on its C-terminal prenylation. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which implicated its role in the tumorigenesis. Studies in rat suggested that this gene may be an immediate-early gene in mitogen-stimulated cells.PRL phosphatases increase cell proliferation by stimulating progression from G1 into S phase. PRL-1 function is regulated in a cell cycle-dependent manner and implicate PRL-1 in regulating progression through mitosis, possibly by modulating spindle dynamics.Synonyms: PRL-1, PTP(CAAXI), PTPCAAX1, Protein tyrosine phosphatase type IVA 1, Protein-tyrosine phosphatase 4a1, Protein-tyrosine phosphatase of regenerating liver 1
    Gene ID
    7803
    NCBI Accession
    NP_003454
    UniProt
    Q93096
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