CLCA1 antibody (Internal Region)

Catalog No. ABIN375029

Product Details anti-CLCA1 Antibody

Target: CLCA1 (Chloride Channel Accessory 1 (CLCA1))

Binding Specificity: AA 872-884, Internal Region

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This CLCA1 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: This antibody reacts to CLCA1.

Purification: Affinity chromatography

Immunogen: Peptide with sequence PETPSPDETSAPC, from the internal region of the protein sequence

Application Details

Application Notes: Peptide ELISA: 1/64000. Western Blot: 0.3 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CLCA1

Target: CLCA1 (Chloride Channel Accessory 1 (CLCA1))

Alternative Name: CLCA1 (CLCA1 Products)

Synonyms: CACC antibody, CACC1 antibody, CLCRG1 antibody, CaCC-1 antibody, GOB5 antibody, hCLCA1 antibody, hCaCC-1 antibody, Clca3 antibody, fi39d11 antibody, wu:fi39d11 antibody, AECC antibody, Clca1 antibody, Clca2 antibody, gob-5 antibody, gob5 antibody, chloride channel accessory 1 antibody, chloride channel antibody, chloride channel protein antibody, CLCA1 antibody, Clca1 antibody, clca1 antibody, clcA1 antibody

Background: CLCA1 belongs to the calcium sensitive chloride conductance protein family. May be involved in mediating calcium-activated chloride conductance. May play critical roles in goblet cell metaplasia, mucus hypersecretion, cystic fibrosis and AHR. May be involved in the regulation of mucus production and/or secretion by goblet cells. Involved in the regulation of tissue inflammation in the innate immune response. May play a role as a tumor suppressor.Synonyms: CACC1, CaCC-1, Calcium-activated chloride channel family member 1, Calcium-activated chloride channel regulator 1

Gene ID: 1179

NCBI Accession: NP_001276

UniProt: A8K7I4