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NDUFS1 antibody (Internal Region)

NDUFS1 Reactivity: Human, Rat, Mouse, Cow, Rabbit, Dog WB, EIA Host: Goat Polyclonal unconjugated
Catalog No. ABIN498087
  • Target See all NDUFS1 Antibodies
    NDUFS1 (NADH Dehydrogenase (Ubiquinone) Fe-S Protein 1, 75kDa (NADH-Coenzyme Q Reductase) (NDUFS1))
    Binding Specificity
    • 15
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 53
    • 35
    • 24
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Rat, Mouse, Cow, Rabbit, Dog
    Host
    • 48
    • 4
    • 1
    Goat
    Clonality
    • 51
    • 2
    Polyclonal
    Conjugate
    • 32
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NDUFS1 antibody is un-conjugated
    Application
    • 44
    • 16
    • 14
    • 13
    • 13
    • 9
    • 8
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Sequence
    C-TEKSATYVNT EGR
    Cross-Reactivity (Details)
    Species reactivity (expected):Rat, Canine (Dog), Bovine and RabbitSpecies reactivity (tested):Human, Mouse.
    Purification
    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
    Immunogen
    Peptide from the internal region of the protein sequence according to NP_004997.4. Genename: NDUFS1
    Top Product
    Discover our top product NDUFS1 Primary Antibody
  • Application Notes
    Peptide ELISA: Detection Limit: 1/64000. Western blot: 0.3-1 μg/mL. Detects a band of Approx 80 kDa in Human Heart and Mouse Heart lysates.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user. Species Reactivity: Tested: Human, Mouse. Expected from sequence similarity: Rat, Canine (Dog), Bovine and RabbitAdd. Information: Calculated Molecular Weight: 79.0 kDa according to NP_004997.4
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    NDUFS1 (NADH Dehydrogenase (Ubiquinone) Fe-S Protein 1, 75kDa (NADH-Coenzyme Q Reductase) (NDUFS1))
    Alternative Name
    NDUFS1 (NDUFS1 Products)
    Synonyms
    5830412M15Rik antibody, 9930026A05Rik antibody, CI-75Kd antibody, CI-75k antibody, PRO1304 antibody, NADH dehydrogenase (ubiquinone) Fe-S protein 1 antibody, NADH:ubiquinone oxidoreductase core subunit S1 antibody, Ndufs1 antibody, NDUFS1 antibody
    Background
    NDUFS1 belongs to the complex I 75 kDa subunit family. Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. Ndufs1 has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. This protein is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized. Mutations in Ndufs1 gene are associated with complex I deficiency.Synonyms: CI-75kD, Complex I-75kD, NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
    Gene ID
    4719
    NCBI Accession
    NP_004997
    UniProt
    P28331
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