IMP3 antibody (Internal Region)

Catalog No. ABIN499130

Product Details anti-IMP3 Antibody

Target: IMP3 (IMP3, U3 Small Nucleolar Ribonucleoprotein (IMP3))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat, Cow, Dog

Host: Goat

Clonality: Polyclonal

Conjugate: This IMP3 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Sequence: C-QRREDYTRYN QLSR

Specificity: Recognizes IMP3.

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat, Pig, Canine (Dog), Bovine.
Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_060755.1. Genename: IMP3

Application Details

Application Notes: Peptide ELISA: Limit Dilution: 1/4000. Western blot: 0.05-0.2 μg/mL. This antibody detects a band of approx. 22 kDa in Human Liverlysates (calculated MW of 21.2 kDa according to NP_060755.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for IMP3

Target: IMP3 (IMP3, U3 Small Nucleolar Ribonucleoprotein (IMP3))

Alternative Name: IMP3 (IMP3 Products)

Synonyms: BRMS2 antibody, C15orf12 antibody, MRPS4 antibody, 1190002L16Rik antibody, AI256594 antibody, RGD1306825 antibody, zgc:56526 antibody, imp3 antibody, IMP3, U3 small nucleolar ribonucleoprotein antibody, IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast) antibody, inositol monophosphatase domain containing 1 antibody, IMP3, U3 small nucleolar ribonucleoprotein L homeolog antibody, IMP3 antibody, Imp3 antibody, imp3 antibody, IMPAD1 antibody, imp3.L antibody

Background: IMP3 (Insulin like growth factor 2 mRNA binding protein 3) is an RNA binding protein which binds to the 5'-UTR of the insulin like growth factor 2 (IGF2) mRNAs and to sequences in the 3'-UTR of CD44 mRNA. It contains several KH domains, which are important in RNA binding and may act as a regulator of mRNA translation and stability.Synonyms: BRMS2, C15orf12, MRPS4, U3 small nucleolar ribonucleoprotein protein IMP3, U3 snoRNP protein IMP3

Gene ID: 55272

NCBI Accession: NP_060755

UniProt: Q9NV31