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CIDEB antibody (C-Term)

CIDEB Reactivity: Mouse WB, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN499629
  • Target See all CIDEB Antibodies
    CIDEB (Cell Death-Inducing DFFA-Like Effector B (CIDEB))
    Binding Specificity
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 22
    • 13
    • 4
    • 2
    Mouse
    Host
    • 23
    • 4
    Rabbit
    Clonality
    • 23
    • 3
    Polyclonal
    Conjugate
    • 23
    • 2
    • 1
    • 1
    This CIDEB antibody is un-conjugated
    Application
    • 19
    • 17
    • 7
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificity
    CIDE-B antibody was raised against a peptide corresponding to amino acids 204 to 219 of murine CIDE-B. It has no cross activity to CIDE-A.
    Purification
    Affinity chromatography purified via peptide column
    Immunogen
    Mouse mCIDE-B (C-Terminus) Peptide
    Isotype
    IgG
    Top Product
    Discover our top product CIDEB Primary Antibody
  • Application Notes
    ELISA. Western Blot: CIDE-B antibody can be used for detection of CIDE-B at 1/500 to 1/1000dilution. An approximately 25 kDa band can be detected.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C.
  • Target
    CIDEB (Cell Death-Inducing DFFA-Like Effector B (CIDEB))
    Alternative Name
    CIDE-B (CIDEB Products)
    Synonyms
    Cide-b antibody, 1110030C18Rik antibody, AI790179 antibody, CIDE-B antibody, cell death-inducing DFFA-like effector b antibody, cell death activator CIDE-B antibody, cell death-inducing DNA fragmentation factor, alpha subunit-like effector B antibody, cideb antibody, CIDEB antibody, Cide-b antibody, Cideb antibody
    Background
    Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase. DFF45/ICAD has been identified as inhibitor of caspase activated DNase DFF40/CAD. DFF45 related proteins CIDE-A and CIDE-B (for cell death-inducing DFF-like effector A and B) were recently identified (1).CIDE contains a new type of domain termed CIDE-N, which has high homology with the regulatory domains of DFF45/ICAD and DFF40/CAD (1,2). Expression of CIDE-B induces apoptosis, which is inhibited by DFF45. CIDE-B is a DFF45-inhibitable effector that promotes cell death and DNA fragmentation. CIDE-B is expressed mainly in liver and at lower levels in spleen, kidney, peripheral blood lymphocytes, and bone marrow (1).Synonyms: CIDE B, CIDEB, Cell Death Activator CIDE-B, Cell Death-Inducing DFFA-Like Effector B
    Gene ID
    12684
    UniProt
    O70303
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