CRMP1 antibody (Intermediate Domain)

Catalog No. ABIN499652

Product Details anti-CRMP1 Antibody

Target: CRMP1 (Collapsin Response Mediator Protein 1 (CRMP1))

Binding Specificity: Intermediate Domain

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRMP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: CRMP1 antibody was raised against a 16 amino acid peptide from near the center of human CRMP1.

Purification: Affinity chromatography purified via peptide column

Immunogen: Virus CRMP1 / Collapsin response mediator protein 1 / DRP-1 / dihydropyropyrimidinase- related protein 1 (Intermediate Domain) Peptide

Isotype: IgG

Application Details

Application Notes: ELISA. Western Blot: CRMP1 antibody can be used for the detection of CRMP1 at 1 - 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C.

Target Details for CRMP1

Target: CRMP1 (Collapsin Response Mediator Protein 1 (CRMP1))

Alternative Name: CRMP1 / DPYSL1 (CRMP1 Products)

Synonyms: CRMP1 antibody, crmp1 antibody, MGC145930 antibody, CRMP 1 antibody, CRMP-1 antibody, PCRMP 1 antibody, PCRMP-1 antibody, PCRMP1 antibody, PfCRMP-1 antibody, DPYSL1 antibody, DRP-1 antibody, DRP1 antibody, ULIP-3 antibody, Dpysl1 antibody, Ulip3 antibody, CRMP1B antibody, collapsin response mediator protein 1 antibody, dihydropyrimidinase-related protein 1 antibody, cysteine repeat modular protein 1, putative antibody, collapsin response mediator protein 1 L homeolog antibody, CRMP1 antibody, crmp1 antibody, LOC100350067 antibody, PfCRMP1 antibody, Crmp1 antibody, crmp1.L antibody

Background: Collapsin-response mediator proteins (CRMPs) are highly expressed in the developing brain where they play major roles in axonal outgrowth, neurite differentiation, and apoptosis (1). Their continued expression in areas of high synaptic remodeling such as the cerebellum, hippocampus, and the olfactory system suggests that these proteins may also be involved in adult brain plasticity (2). CRMP-1 was initially identified as a dihydro-pyrimidinase expressed exclusively in brain (3), later studies have shown that it is involved with neurotrophin (NT) 3-induced neurite formation and outgrowth (4). CRMP-1 localization switches from axonal to somatodendritic when neurons reach functional maturity, suggesting that it is involved in early neuronal differentiation as well as in later processes related to the survival or death of the newly generated neurons (5).Synonyms: Collapsin response mediator protein 1, DRP-1, Dihydropyrimidinase-related protein 1, ULIP3, Unc-33-like phosphoprotein 3

Gene ID: 1400

UniProt: Q14194