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FKBP15 antibody (N-Term)

FKBP15 Reactivity: Human, Mouse, Rat WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN499840
  • Target See all FKBP15 Antibodies
    FKBP15 (FK506 Binding Protein 15, 133kDa (FKBP15))
    Binding Specificity
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 4
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 4
    Rabbit
    Clonality
    • 4
    Polyclonal
    Conjugate
    • 4
    This FKBP15 antibody is un-conjugated
    Application
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody reacts to FKBP15.
    Purification
    Affinity chromatography purified via peptide column
    Immunogen
    FKBP15 antibody was raised against a 15 amino acid peptide from near the amino terminus of human FKBP15.
    Isotype
    IgG
  • Application Notes
    ELISA. Western Blot: 1 - 2 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C.
  • Target
    FKBP15 (FK506 Binding Protein 15, 133kDa (FKBP15))
    Alternative Name
    FKBP15 (FKBP15 Products)
    Synonyms
    KIAA0674 antibody, DKFZp469F024 antibody, BB131447 antibody, C430014M02Rik antibody, FKBO133 antibody, FKBP-133 antibody, FKBP-15 antibody, FKBP133 antibody, mKIAA0674 antibody, RGD1304816 antibody, PPP1R76 antibody, FK506 binding protein 15 antibody, si:ch211-208h16.4 antibody, FKBP15 antibody, si:ch211-208h16.4 antibody, Fkbp15 antibody
    Background
    FKBP15, also known as FKBP133, is a member of the FK506-binding protein family, a group of proteins initially identified as immunophilins, targets for the immunosupressant drugs FK506 and Rapamycin. FKBP15 is expressed in the developing nervous system and contains a domain similar to Wiskott-Aldrich syndrome protein homology region 1 (WH1) in addition to the FK506-binding protein motif. FKBP15 is distributed along the axonal shafts and partially co-localizes with F-actin in the growth cones of dorsal root ganglion neurons, overexpression of FKBP15 resulted in the number of filopodia in transfected neurons, suggesting that FKBP15 modulates growth cone behavior. FKBP15 has also been shown to associate with both microtubules and the actin filament systems and disruption of its expression by RNAi resulted in delayed transport of early endosomes in HeLa cells indicating that FKBP15 is also involved in the transport of early endosomes. At least three isoforms of FKBP15 are known to exist.Synonyms: 133 kDa FK506-binding protein, FK506-binding protein 15, FKBP133, KIAA0674, WAFL, WASP and FKBP-like
    Gene ID
    23307
    NCBI Accession
    NP_056073
    UniProt
    Q5T1M5
    Pathways
    SARS-CoV-2 Protein Interactome
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