Klra2 antibody (C-Term)
Klra2
Reactivity: Mouse, Rat
WB, IHC (p), EIA
Host: Rabbit
Polyclonal
unconjugated
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- Target See all Klra2 Antibodies
- Klra2 (Killer Cell Lectin-Like Receptor, Subfamily A, Member 2 (Klra2))
- Binding Specificity
- C-Term
- Reactivity
- Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Klra2 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- Cross-Reactivity (Details)
- Species reactivity (tested):Human, mouse
- Purification
- Peptide affinity chromatography
- Immunogen
- KLRA2 antibody was raised against a 14 amino acid peptide near the carboxy terminus of mouse KLRA2.
- Isotype
- IgG
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- Application Notes
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ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Buffer
- PBS containing 0.02 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- Target
- Klra2 (Killer Cell Lectin-Like Receptor, Subfamily A, Member 2 (Klra2))
- Alternative Name
- KLRA2 (Klra2 Products)
- Synonyms
- Klra30 antibody, Ly49b antibody, Ly49i6 antibody, killer cell lectin-like receptor, subfamily A, member 2 antibody, Klra2 antibody
- Background
- KLRA2 (also known as Ly49B) is a member of the LY49 family of receptors in Natural Killer (NK) cells that bind to major histocompatibility complex (MHC) class 1. These proteins are classified as either activating or inhibitory receptors based on whether they possess an immunoreceptor tyrosine-based inhibitory motif (ITIM) in their cytoplasmic region (for inhibitory receptors), or an immunoreceptor tyrosine-based activation motif (ITAM) that transmits activating signals resulting in phosphorylation of several substrates. KLRA2 is thought to be an inhibitory receptor and associates with the protein tyrosine phosphatases SHP1, SHP2, and SHIP in transfected cells.Synonyms: Killer cell lectin-like receptor 2, Ly49-b, Ly49b, Lymphocyte antigen 49b, T-cell surface glycoprotein Ly-49B
- UniProt
- Q60660
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