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MYBPC2 antibody (C-Term)

MYBPC2 Reactivity: Human, Mouse WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN500298
  • Target See all MYBPC2 Antibodies
    MYBPC2 (Myosin Binding Protein C, Fast Type (MYBPC2))
    Binding Specificity
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 16
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Mouse
    Host
    • 16
    Rabbit
    Clonality
    • 16
    Polyclonal
    Conjugate
    • 12
    • 2
    • 1
    • 1
    This MYBPC2 antibody is un-conjugated
    Application
    • 10
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Cross-Reactivity (Details)
    Species reactivity (tested):Human, mouse
    Purification
    Peptide affinity chromatography
    Immunogen
    MYBPC2 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human MYBPC2.
    Isotype
    IgG
    Top Product
    Discover our top product MYBPC2 Primary Antibody
  • Application Notes
    ELISA. Western blot: 1 - 2 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store the antibody (in aliquots) at -20 °C.
  • Emmanuele, Kubota, Garcia-Diaz, Garone, Akman, Sánchez-Gutiérrez, Escudero, Kariya, Homma, Tanji, Quinzii, Hirano: "Fhl1 W122S causes loss of protein function and late-onset mild myopathy." in: Human molecular genetics, Vol. 24, Issue 3, pp. 714-26, (2015) (PubMed).

  • Target
    MYBPC2 (Myosin Binding Protein C, Fast Type (MYBPC2))
    Alternative Name
    MYBPC2 (MYBPC2 Products)
    Synonyms
    MYBPC antibody, MYBPCF antibody, im:7137115 antibody, im:7150089 antibody, zgc:110761 antibody, myosin binding protein C, fast-type antibody, myosin binding protein C, fast type antibody, myosin-binding protein C, fast-type antibody, myosin binding protein C, fast type b antibody, Mybpc2 antibody, MYBPC2 antibody, LOC520988 antibody, mybpc2b antibody
    Background
    Myosin binding protein C (MYBPC) is a component of the thick filament of striated muscle, with the fast-type isoform designated MYBPC2. Both the fast-type and slow-type MYBPC protein contains seven immunoglobulin C2 motifs and three fibronectin type-III repeats. MYBPC2 is typically required for strong contractions and functions under anaerobic conditions. It is more similar to the cardiac isoform (MYBPC3) than to the slow-type isoform (MYBPC1) in terms of pCa50-indexed force development, length-independent cooperativity and length dependent activation. It has been suggested that in cardiac and fast muscle MYBPC2 contributes to an internal load, possibly by binding to actin via its N-terminal region.Synonyms: C-protein, Fast MyBP-C, MYBPCF, Myosin-binding protein C, skeletal muscle fast isoform
    Gene ID
    4606
    NCBI Accession
    NP_004524
    UniProt
    Q14324
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