4932442K08Rik antibody, AW049283 antibody, AW413338 antibody, CCPG antibody, Pgcc1 antibody, mKIAA1838 antibody, KIAA1838 antibody, PGCC1 antibody, dJ894D12.1 antibody, RGD1310304 antibody, family with sequence similarity 120B antibody, family with sequence similarity 120, member B antibody, FAM120B antibody, Fam120b antibody
Background
The transcription factor peroxisome proliferator-activated receptor gamma (PPARg) plays essential roles in adipogenesis by regulating adipocyte-specific genes through association of various co-factors. One such co-factor, PGCC1 (also known as FAM120B), is widely expressed in adult tissues and throughout embryonic development. Overexpression of this protein in OP9 pre-adipocytes promoted their differentiation into adipocytes, and knockdown of PGCC1 expression through RNA interference blocked this process. PGCC1 is homologous to C9orf10 (also known as FAM120A) and has been mapped to chromosome Xp11.22. At least two isoforms of PGCC1 are known to exist.Synonyms: CCPG, Constitutive coactivator of PPAR-gamma, Constitutive coactivator of PPARG, Constitutive coactivator of peroxisome proliferator-activated receptor gamma, FAM120B, KIAA1838, PGCC1, PPARG constitutive coactivator 1, Protein FAM120B