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DLGAP3 antibody (C-Term)

DLGAP3 Reactivity: Human, Mouse, Rat WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN500656
  • Target See all DLGAP3 Antibodies
    DLGAP3 (Discs, Large (Drosophila) Homolog-Associated Protein 3 (DLGAP3))
    Binding Specificity
    • 8
    • 8
    • 6
    • 1
    • 1
    C-Term
    Reactivity
    Human, Mouse, Rat
    Host
    • 17
    Rabbit
    Clonality
    • 17
    Polyclonal
    Conjugate
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    This DLGAP3 antibody is un-conjugated
    Application
    • 17
    • 13
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects SAPAP3.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human, mouse, rat
    Purification
    Peptide affinity chromatography
    Immunogen
    SAPAP3 antibody was raised against a 18 amino acid peptide from near the carboxy terminus of human SAPAP3.
    Isotype
    IgG
    Top Product
    Discover our top product DLGAP3 Primary Antibody
  • Application Notes
    ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target
    DLGAP3 (Discs, Large (Drosophila) Homolog-Associated Protein 3 (DLGAP3))
    Alternative Name
    DLGAP3 (DLGAP3 Products)
    Synonyms
    DAP3 antibody, SAPAP3 antibody, BC058433 antibody, DAP-3 antibody, Prpl8 antibody, Sapap3 antibody, Dap3 antibody, DLG associated protein 3 antibody, discs, large (Drosophila) homolog-associated protein 3 antibody, DLGAP3 antibody, Dlgap3 antibody, dlgap3 antibody
    Background
    SAP90/PSD-95-associated protein 3 (SAPAP3, also known as DLGAP3) is a member of a protein family whose members specifically interact with PSD-95/SAP90, a membrane-associated guanylate kinase localized at postsynaptic density (PSD) in neuronal cells. Like the other SAPAP proteins, SAPAP3 is thought to be an adaptor protein that also interacts with different synaptic scaffolding proteins, cytoskeletal and signaling components, such as focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2). Both SAPAP3 protein and mRNA are targeted to dendrites, whereas SAPAP1, -2, and -4 mRNAs are detected mainly in cell bodies. Recent experiments have suggested that SAPAP3 may be involved in obsessive-compulsive disorder (OCD), as mice lacking SAPAP3 exhibited OCD-like symptoms which could be relieved by lentiviral-mediated selective expression of SAPAP3 in the striatum of SAPAP3-mutant mice. At least two isoforms are known to exist.Synonyms: DAP-3, DAP3, Disks large-associated protein 3, PSD-95/SAP90-binding protein 3, SAP90/PSD-95-associated protein 3, SAPAP3
    Gene ID
    58512
    UniProt
    O95886
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