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SATB2 antibody (N-Term)

SATB2 Reactivity: Human, Mouse, Rat WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN500674
  • Target See all SATB2 Antibodies
    SATB2 (SATB Homeobox 2 (SATB2))
    Binding Specificity
    • 16
    • 8
    • 7
    • 7
    • 6
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 68
    • 34
    • 28
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 59
    • 9
    Rabbit
    Clonality
    • 45
    • 23
    Polyclonal
    Conjugate
    • 33
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This SATB2 antibody is un-conjugated
    Application
    • 50
    • 23
    • 16
    • 14
    • 14
    • 10
    • 9
    • 8
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects SATB2 at N-term. It will not cross-react with SATB1.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human, mouse, rat
    Purification
    Peptide affinity chromatography
    Immunogen
    SATB2 antibody was raised against a 16 amino acid peptide near the amino terminus of the human SATB2.
    Isotype
    IgG
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  • Application Notes
    ELISA. Western blot: 2 - 4 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target
    SATB2 (SATB Homeobox 2 (SATB2))
    Alternative Name
    SATB2 (SATB2 Products)
    Synonyms
    RGD1562369 antibody, mKIAA1034 antibody, SATB homeobox 2 antibody, special AT-rich sequence binding protein 2 antibody, SATB2 antibody, satb2 antibody, Satb2 antibody
    Background
    Human special AT-rich sequence-binding protein-2 (SATB2) is a nuclear matrix/scaffold-associated region DNA-binding protein. Like its homolog SATB1, SATB2 selectively binds double-stranded, special AT-rich DNA sequences, but is expressed primarily in a subset of postmitotic, differentiating neurons in the neocortex. Mice deficient in SATB exhibit craniofacial abnormalities and defects in osteoblast differentiation and function. SATB2 also interacts with and enhances the activity of Runx2 and ATF4, two transcription factors that regulate osteoblast differentiation, indicating that SATB2 acts as a molecular node in a transcriptional network regulating skeletal development and osteoblast differentiation. Recent experiments have shown that SATB2 interacts with histone deacetylase 1 and metastasis-associated protein 2, two proteins that are involved in chromatin remodeling, suggesting that SATB2 may also be involved in mediating epigenetic influences during cortical development. At least two isoforms of SATB2 are known to exist.Synonyms: DNA-binding protein SATB2, KIAA1034, Special AT-rich sequence-binding protein 2
    Gene ID
    23314
    UniProt
    Q9UPW6
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