CIAO1 antibody (C-Term)

Catalog No. ABIN1109505

Product Details anti-CIAO1 Antibody

Target: CIAO1 (Cytosolic Iron-Sulfur Protein Assembly 1 (CIAO1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CIAO1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LSGFHSRTIY DIAWCQLTGA LATACGDDAI RVFQEDPNSD PQQPTFSLTA

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat, Dog, BovineSpecies reactivity (tested):Human

Purification: Purified using Protein A affinity column

Immunogen: The immunogen for anti-WDR39 antibody: synthetic peptide directed towards the C terminal of human WDR39

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Add 100 μL of distilled water to a final concentration of 1 mg/mL.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Target Details for CIAO1

Target: CIAO1 (Cytosolic Iron-Sulfur Protein Assembly 1 (CIAO1))

Alternative Name: WDR39 / CIAO1 (CIAO1 Products)

Synonyms: CG12797 antibody, Dmel\\CG12797 antibody, DDBDRAFT_0190506 antibody, DDBDRAFT_0266672 antibody, DDB_0190506 antibody, DDB_0266672 antibody, CIA1 antibody, WDR39 antibody, AW210570 antibody, Wdr39 antibody, wdr39 antibody, zgc:55911 antibody, zgc:77394 antibody, CG12797 gene product from transcript CG12797-RA antibody, WD40 protein Ciao1 antibody, CIAO1 antibody, WD40 repeat-containing protein antibody, cytosolic iron-sulfur assembly component 1 antibody, cytosolic iron-sulfur protein assembly 1 antibody, Ciao1 antibody, cgd1_2230 antibody, CC1G_05316 antibody, ciao1 antibody, CIAO1 antibody

Background: WDR39 is a member of the WD40 family of proteins. WDR39 specifically interacts with WT1 both in vitro and in vivo. This interaction results in a decrease in transcriptional activation mediated by WT1. WDR39 does not inhibit binding of WT1 to its consensus nucleotide sequence and does not affect the repression activity of WT1. Thus, WDR39 appears to specifically modulate the transactivation activity of WT1 and may function to regulate the physiological functions of WT1 in cell growth and differentiation.Synonyms: WD repeat-containing protein 39

Gene ID: 9391

NCBI Accession: NP_004795