Vascular Cell Adhesion Molecule 1 (VCAM1) (AA 215-457) antibody

Details for Product No. ABIN556360
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Antigen
Synonyms fi76d06, wu:fi76d06, zgc:158875, VCAM1, CD106, INCAM-100, Vcam-1, VCAM1B
Epitope
AA 215-457
(7), (6), (5), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(221), (134), (60), (15), (5), (4), (3), (1)
Host
Rabbit
(178), (86), (76), (10), (3), (3)
Clonality
Polyclonal
Conjugate
Un-conjugated
(49), (32), (17), (9), (5), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(210), (112), (95), (84), (72), (71), (37), (30), (29), (25), (21), (7), (6), (6), (3), (2), (2), (1)
Pubmed 2 references available
Quantity 0.1 mL
Shipping to United States (Change)
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Catalog No. ABIN556360
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Immunogen Recombinant fragment corresponding to a region within amino acids 215 and 457 of VCAM1
Isotype IgG
Predicted Reactivity Human (100%)
Characteristics Cellular Localization: Membrane, Single-pass type I membrane protein
Purification Purified by antigen-affinity chromatography..
Alternative Name CD106 / VCAM1
Background This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Two alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq]
Synonyms: CD106 antibody, DKFZp779G2333 antibody, INCAM-100 antibody, MGC99561 antibody, VCAM1 antibody, vascular cell adhesion protein 1 antibody, CD106 antigen antibody, vascular cell adhesion molecule 1 antibody
Molecular Weight 81 kDa
UniProt P19320
Research Area CD Antigens, Surface Receptors of Immune Cells
Comment

Positive Controls: Target recombinant protein

Restrictions For Research Use only
Format Liquid
Concentration 0.59 mg/mL
Buffer 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid multiple freeze-thaw cycles.
Storage -20 °C
Storage Comment Keep as concentrated solution. Aliquot and store at -20°C or below.
Product cited in: Rosen, Siddique, Patterson et al.: "Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis." in: Nature, Vol. 362, Issue 6415, pp. 59-62, 1993 (PubMed).

Reaume, Elliott, Hoffman et al.: "Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury." in: Nature genetics, Vol. 13, Issue 1, pp. 43-7, 1996 (PubMed).

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