Hydroxyprostaglandin Dehydrogenase 15-(NAD) (HPGD) (AA 1-202) antibody

Details for Product No. ABIN556459
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Antigen
Synonyms MGC80546, MGC79454, 15-PGDH, AV026552, PGDH, PGDH1, PHOAR1, SDR36C1
Epitope
AA 1-202
(21), (7), (4), (3), (3), (2), (1), (1)
Reactivity
Human
(80), (21), (15), (13), (12), (2), (1), (1)
Host
Rabbit
(54), (25), (8)
Clonality
Polyclonal
Conjugate
Un-conjugated
(5), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(54), (29), (27), (15), (13), (10), (8), (6), (5), (3)
Pubmed 2 references available
Quantity 0.1 mL
Shipping to United States (Change)
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Catalog No. ABIN556459
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Immunogen Recombinant fragment corresponding to a region within amino acids 1 and 202 of 15-PGDH
Isotype IgG
Predicted Reactivity Human (100%)
Characteristics Cellular Localization: Cytoplasm
Purification Purified by antigen-affinity chromatography..
Alternative Name HPGD
Background This gene encodes a member of the short-chain nonmetalloenzyme alcohol dehydrogenase protein family. The encoded enzyme is responsible for the metabolism of prostaglandins, which function in a variety of physiologic and cellular processes such as inflammation. Mutations in this gene result in primary autosomal recessive hypertrophic osteoarthropathy and cranioosteoarthropathy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Synonyms: 15-PGDH antibody, PGDH antibody, PGDH1 antibody, SDR36C1 antibody, HPGD antibody, prostaglandin dehydrogenase 1 antibody, NAD+-dependent 15-hydroxyprostaglandin dehydrogenase antibody, 15-hydroxyprostaglandin dehydrogenase [NAD+] antibody, "short chain dehydrogenase/reductase family 36C, member 1 antibody", hydroxyprostaglandin dehydrogenase 15-(NAD) antibody
Molecular Weight 29 kDa
UniProt P15428
Comment

Positive Controls: Target recombinant protein

Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid multiple freeze-thaw cycles.
Storage -20 °C
Storage Comment Keep as concentrated solution. Aliquot and store at -20°C or below.
Product cited in: Faucheu, Diu, Chan et al.: "A novel human protease similar to the interleukin-1 beta converting enzyme induces apoptosis in transfected cells." in: The EMBO journal, Vol. 14, Issue 9, pp. 1914-22, 1995 (PubMed).

Munday, Vaillancourt, Ali et al.: "Molecular cloning and pro-apoptotic activity of ICErelII and ICErelIII, members of the ICE/CED-3 family of cysteine proteases." in: The Journal of biological chemistry, Vol. 270, Issue 26, pp. 15870-6, 1995 (PubMed).

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