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Ketohexokinase (KHK) (AA 34-247) antibody

Details for Product No. ABIN556462, Supplier: Login to see
Antigen
  • wu:fj68h03
  • zgc:92219
  • zgc:92626
  • KHK
  • khk
  • KETHPRO
Epitope
AA 34-247
20
20
9
6
2
2
2
2
1
1
1
1
Reactivity
Human
108
30
22
1
1
Host
Rabbit
75
31
2
Clonality
Polyclonal
Conjugate
Un-conjugated
5
5
5
4
4
4
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
88
43
22
20
15
15
11
7
3
2
1
Supplier
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Immunogen Recombinant fragment corresponding to a region within amino acids 34 and 247 of Ketohexokinase
Isotype IgG
Predicted Reactivity Human (100%)
Purification Purified by antigen-affinity chromatography..
Alternative Name Ketohexokinase (KHK Antibody Abstract)
Background This gene encodes ketohexokinase that catalyzes conversion of fructose to fructose-1-phosphate. The product of this gene is the first enzyme with a specialized pathway that catabolizes dietary fructose. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]
Synonyms: KHK antibody, ketohexokinase antibody, hepatic fructokinase antibody, ketohexokinase (fructokinase) antibody
Molecular Weight 33 kDa
UniProt P50053
Pathways
Comment

Positive Controls: Target recombinant protein

Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid multiple freeze-thaw cycles.
Storage -20 °C
Storage Comment Keep as concentrated solution. Aliquot and store at -20°C or below.
Product cited in: Magae, Wu, Illenye et al.: "Nuclear localization of DP and E2F transcription factors by heterodimeric partners and retinoblastoma protein family members." in: Journal of cell science, Vol. 109 ( Pt 7), Issue 25, pp. 1717-26, 1997 (PubMed).

Huber, Edwards, Goodhart et al.: "Transcription factor E2F binds DNA as a heterodimer." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 90, Issue 8, pp. 3525-9, 1993 (PubMed).

Helin, Wu, Fattaey et al.: "Heterodimerization of the transcription factors E2F-1 and DP-1 leads to cooperative trans-activation." in: Genes & development, Vol. 7, Issue 10, pp. 1850-61, 1993 (PubMed).

Jooss, Lam, Bybee et al.: "Proto-oncogenic properties of the DP family of proteins." in: Oncogene, Vol. 10, Issue 8, pp. 1529-36, 1995 (PubMed).