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Ketohexokinase (KHK) (AA 34-247) antibody

Details for Product No. ABIN556462
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Antigen
Synonyms wu:fj68h03, zgc:92219, zgc:92626, KHK, khk, KETHPRO
Epitope
AA 34-247
(12), (12), (8), (6), (2), (2), (2), (1)
Reactivity
Human
(69), (23), (15), (13), (12), (1)
Host
Rabbit
(48), (22), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(55), (26), (15), (13), (10), (9), (7), (3), (2), (1)
Pubmed 4 references available
Quantity 0.1 mL
Shipping to United States (Change)
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Catalog No. ABIN556462
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Immunogen Recombinant fragment corresponding to a region within amino acids 34 and 247 of Ketohexokinase
Isotype IgG
Predicted Reactivity Human (100%)
Purification Purified by antigen-affinity chromatography..
Alternative Name Ketohexokinase
Background This gene encodes ketohexokinase that catalyzes conversion of fructose to fructose-1-phosphate. The product of this gene is the first enzyme with a specialized pathway that catabolizes dietary fructose. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]
Synonyms: KHK antibody, ketohexokinase antibody, hepatic fructokinase antibody, ketohexokinase (fructokinase) antibody
Molecular Weight 33 kDa
UniProt P50053
Comment

Positive Controls: Target recombinant protein

Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid multiple freeze-thaw cycles.
Storage -20 °C
Storage Comment Keep as concentrated solution. Aliquot and store at -20°C or below.
Product cited in: Jooss, Lam, Bybee et al.: "Proto-oncogenic properties of the DP family of proteins." in: Oncogene, Vol. 10, Issue 8, pp. 1529-36, 1995 (PubMed).

Helin, Wu, Fattaey et al.: "Heterodimerization of the transcription factors E2F-1 and DP-1 leads to cooperative trans-activation." in: Genes & development, Vol. 7, Issue 10, pp. 1850-61, 1993 (PubMed).

Huber, Edwards, Goodhart et al.: "Transcription factor E2F binds DNA as a heterodimer." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 90, Issue 8, pp. 3525-9, 1993 (PubMed).

Magae, Wu, Illenye et al.: "Nuclear localization of DP and E2F transcription factors by heterodimeric partners and retinoblastoma protein family members." in: Journal of cell science, Vol. 109 ( Pt 7), Issue 25, pp. 1717-26, 1997 (PubMed).

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