You are viewing an incomplete version of our website. Please click to reload the website as full version.

RAB8A antibody (RAB8A, Member RAS Oncogene Family) (AA 1-134)

Details for Product anti-RAB8A Antibody No. ABIN556466, Supplier: Login to see New
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Synonyms rab8A, DDBDRAFT_0206521, DDBDRAFT_0214885, DDB_0206521, DDB_0214885, HSH2D, mel, rab8, c-mel, MEL, RAB8, zgc:162699, AA409338, Mel, Rab8
AA 1-134
(21), (4), (2), (2), (2), (2), (1), (1), (1), (1)
(58), (20), (19), (9), (6), (2), (2), (2), (1), (1), (1), (1)
(28), (22), (8)
This RAB8A antibody is un-conjugated
(1), (1), (1), (1), (1), (1), (1)
Western Blotting (WB)
(53), (30), (10), (8), (7), (3), (2), (2), (1)
Pubmed 2 references available
Supplier Login to see New
Catalog number from supplier Login to see New
Quantity 0.1 mL
Shipping to United States ( )
Immunogen Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 134 of RAB8A
Isotype IgG
Predicted Reactivity Human (100%), Mouse (100%), Rat (100%), Dog (100%), Pig (100%), Sheep (100%), Chimpanzee (100%), Bovine (100%)
Characteristics Cellular Localization: Cell membrane, Lipid-anchor, Cytoplasmic side
Purification Purified by antigen-affinity chromatography..
Alternative Name RAB8A (RAB8A Antibody Abstract)
Background The protein encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. This protein shares 97%, 96%, and 51% similarity with the dog RAB8, mouse MEL, and mouse YPT1 proteins, respectively and contains the 4 GTP/GDP-binding sites that are present in all the RAS proteins. The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins. However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins. Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrable. This oncogene is located 800 kb distal to MY09B on chromosome 19p13.1. [provided by RefSeq]
Synonyms: MEL antibody, RAB8 antibody, RAB8A antibody, mel transforming oncogene (derived from cell line NK14)- RAB8 homolog antibody, oncogene c-mel antibody, mel transforming oncogene (RAB8 homolog) antibody, ras-related protein Rab-8A antibody, ras-associated protein RAB8 antibody, mel transforming oncogene (derived from cell line NK14) antibody, "RAB8A, member RAS oncogene family antibody"
Molecular Weight 24 kDa
Research Area Signaling

Positive Controls: Target recombinant protein

Restrictions For Research Use only
Format Liquid
Concentration 0.53 mg/mL
Buffer 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid multiple freeze-thaw cycles.
Storage -20 °C
Storage Comment Keep as concentrated solution. Aliquot and store at -20°C or below.
Background publications Thome, Schneider, Hofmann et al.: "Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors." in: Nature, Vol. 386, Issue 6624, pp. 517-21, 1997 (PubMed).

Muzio, Chinnaiyan, Kischkel et al.: "FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex." in: Cell, Vol. 85, Issue 6, pp. 817-27, 1996 (PubMed).

Catalog No. ABIN556466
Contact our Customer Service for availability and price in your country.

Order hotline:

  • +1 877 302 8632
  • +1 888 205 9894 (TF)