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Methylenetetrahydrofolate Reductase (NAD(P)H) (MTHFR) (AA 21-248) antibody

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AA 21-248
(26), (17), (13), (13), (12), (10), (6), (5), (4), (2), (2), (1), (1), (1), (1), (1), (1), (1)
(88), (29), (21), (4), (2), (2), (2)
(52), (26), (19)
(5), (5), (5), (4), (4), (4), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Western Blotting (WB)
(70), (57), (11), (8), (8), (3), (2), (2), (1), (1)
Pubmed 5 references available
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Quantity 0.1 mL
Shipping to United States ( )
Immunogen Recombinant fragment corresponding to a region within amino acids 21 and 248 of MTHFR
Isotype IgG
Predicted Reactivity Mouse (89%), Bovine (89%)
Purification Purified by antigen-affinity chromatography..
Alternative Name MTHFR (MTHFR Antibody Abstract)
Background Methylenetetrahydrofolate reductase (EC catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a cosubstrate for homocysteine remethylation to methionine.[supplied by OMIM]
Synonyms: MTHFR antibody, "5,10-methylenetetrahydrofolate reductase (NADPH) antibody", methylenetetrahydrofolate reductase antibody, methylenetetrahydrofolate reductase (NAD(P)H) antibody
Molecular Weight 75 kDa
UniProt P42898
Research Area Signaling, Metabolism, Amino Acids

Positive Controls: 293T

Restrictions For Research Use only
Format Liquid
Concentration 0.63 mg/mL
Buffer 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid multiple freeze-thaw cycles.
Storage -20 °C
Storage Comment Keep as concentrated solution. Aliquot and store at -20°C or below.
Supplier Images
Western Blotting (WB) image for anti-Methylenetetrahydrofolate Reductase (NAD(P)H) (MTHFR) (AA 21-248) antibody (ABIN556468) anti-Methylenetetrahydrofolate Reductase (NAD(P)H) (MTHFR) (AA 21-248) antibody
Product cited in: Wang, Wang, Hernandez et al.: "Regulation of TRAIL expression by the phosphatidylinositol 3-kinase/Akt/GSK-3 pathway in human colon cancer cells." in: The Journal of biological chemistry, Vol. 277, Issue 39, pp. 36602-10, 2002 (PubMed).

Mariani, Matiba, Armandola et al.: "Interleukin 1 beta-converting enzyme related proteases/caspases are involved in TRAIL-induced apoptosis of myeloma and leukemia cells." in: The Journal of cell biology, Vol. 137, Issue 1, pp. 221-9, 1997 (PubMed).

Marsters, Pitti, Donahue et al.: "Activation of apoptosis by Apo-2 ligand is independent of FADD but blocked by CrmA." in: Current biology : CB, Vol. 6, Issue 6, pp. 750-2, 1997 (PubMed).

Background publications Sheridan, Marsters, Pitti et al.: "Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors." in: Science (New York, N.Y.), Vol. 277, Issue 5327, pp. 818-21, 1997 (PubMed).

Pitti, Marsters, Ruppert et al.: "Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family." in: The Journal of biological chemistry, Vol. 271, Issue 22, pp. 12687-90, 1996 (PubMed).

Catalog No. ABIN556468

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