V-Yes-1 Yamaguchi Sarcoma Viral Oncogene Homolog 1 (YES1) (AA 1-220) antibody

Details for Product No. ABIN556510
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Antigen
Synonyms YES1, c-yes, hst441, p61-yes, yes, HsT441, P61-YES, Yes, p61-Yes, YES, c-Yes, p60c-yes
Epitope
AA 1-220
(17), (12), (12), (8), (7), (6), (5), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Reactivity
Human
(104), (43), (38), (37), (36), (36), (36), (24), (1), (1)
Host
Rabbit
(79), (23), (3)
Clonality
Polyclonal
Conjugate
Un-conjugated
(7), (6), (6), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3)
Application
Western Blotting (WB)
(75), (50), (30), (20), (18), (8), (4), (4), (3), (3), (1), (1)
Pubmed 2 references available
Quantity 0.1 mL
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Catalog No. ABIN556510
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Immunogen Recombinant fragment contain a sequence corresponding to a region within amino acids 1 and 220 of c-Yes
Isotype IgG
Predicted Reactivity Human (100%)
Characteristics Cellular Localization: Cytoplasm , cytosol
Purification Purified by antigen-affinity chromatography..
Alternative Name YES1
Background This gene is the cellular homolog of the Yamaguchi sarcoma virus oncogene. The encoded protein has tyrosine kinase activity and belongs to the src family of proteins. This gene lies in close proximity to thymidylate synthase gene on chromosome 18, and a corresponding pseudogene has been found on chromosome 22. [provided by RefSeq]
Synonyms: HsT441 antibody, P61-YES antibody, Yes antibody, c-yes antibody, YES1 antibody, proto-oncogene c-Yes antibody, tyrosine-protein kinase Yes antibody, Yamaguchi sarcoma oncogene antibody, cellular yes-1 protein antibody, proto-oncogene tyrosine-protein kinase YES antibody, v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 antibody
Molecular Weight 61 kDa
UniProt P07947
Research Area Transcription Factors
Comment

Positive Controls: Target recombinant protein

Restrictions For Research Use only
Format Liquid
Concentration 0.37 mg/mL
Buffer 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid multiple freeze-thaw cycles.
Storage -20 °C
Storage Comment Keep as concentrated solution. Aliquot and store at -20°C or below.
Product cited in: Duan, Chinnaiyan, Hudson et al.: "ICE-LAP3, a novel mammalian homologue of the Caenorhabditis elegans cell death protein Ced-3 is activated during Fas- and tumor necrosis factor-induced apoptosis." in: The Journal of biological chemistry, Vol. 271, Issue 3, pp. 1621-5, 1996 (PubMed).

Cohen: "Caspases: the executioners of apoptosis." in: The Biochemical journal, Vol. 326 ( Pt 1), Issue 5693, pp. 1-16, 1997 (PubMed).

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