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ABO Blood Group (Transferase A, alpha 1-3-N-Acetylgalactosaminyltransferase, Transferase B, alpha 1-3-Galactosyltransferase) (ABO) (AA 95-299) antibody

Details for Product No. ABIN556532
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Antigen
Synonyms NAGAT, A3GALNT, A3GALT1, GTB, Abo
Epitope
AA 95-299
(8), (7), (3), (1), (1), (1), (1), (1)
Reactivity
Human
(21), (6), (4)
Host
Rabbit
(17), (5)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(20), (8), (4), (1)
Pubmed 5 references available
Quantity 0.1 mL
Shipping to United States (Change)
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Catalog No. ABIN556532
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Immunogen Recombinant protein fragment contain a sequence corresponding to a region within amino acids 95 and 299 of ABO
Isotype IgG
Characteristics Cellular Localization: Golgi apparatus , Golgi stack membrane , Secreted
Purification Purified by antigen-affinity chromatography..
Alternative Name ABO
Background This gene encodes proteins related to the first discovered blood group system, ABO. Which allele is present in an individual determines the blood group. The 'O' blood group is caused by a deletion of guanine-258 near the N-terminus of the protein which results in a frameshift and translation of an almost entirely different protein. Individuals with the A, B, and AB alleles express glycosyltransferase activities that convert the H antigen into the A or B antigen. Other minor alleles have been found for this gene. [provided by RefSeq]
Synonyms: A3GALNT antibody, A3GALT1 antibody, GTB antibody, NAGAT antibody, ABO antibody, "B(A) alpha-1,3-galactosyltransferase antibody", glycoprotein-fucosylgalactoside alpha-galactosyltransferase antibody, ABO glycosyltransferase antibody, fucosylglycoprotein 3-alpha-galactosyltransferase antibody, histo-blood group A2 transferase antibody, histo-blood group B transferase antibody, histo-blood group A transferase antibody, glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase antibody, histo-blood group ABO system transferase antibody, fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase antibody, "ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase, transferase B, alpha 1-3-galactosyltransferase) antibody"
Molecular Weight 41 kDa
Comment

Positive Controls: Target recombinant protein

Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid multiple freeze-thaw cycles.
Storage -20 °C
Storage Comment Keep as concentrated solution. Aliquot and store at -20°C or below.
Product cited in: DiDonato, Hayakawa, Rothwarf et al.: "A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB." in: Nature, Vol. 388, Issue 6642, pp. 548-54, 1997 (PubMed).

Mercurio, Zhu, Murray et al.: "IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation." in: Science (New York, N.Y.), Vol. 278, Issue 5339, pp. 860-6, 1997 (PubMed).

Woronicz, Gao, Cao et al.: "IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK." in: Science (New York, N.Y.), Vol. 278, Issue 5339, pp. 866-9, 1997 (PubMed).

Nakano, Shindo, Sakon et al.: "Differential regulation of IkappaB kinase alpha and beta by two upstream kinases, NF-kappaB-inducing kinase and mitogen-activated protein kinase/ERK kinase kinase-1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, Issue 7, pp. 3537-42, 1998 (PubMed).

Ling, Cao, Goeddel: "NF-kappaB-inducing kinase activates IKK-alpha by phosphorylation of Ser-176." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, Issue 7, pp. 3792-7, 1998 (PubMed).

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