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RNA Binding Motif, Single Stranded Interacting Protein 2 (RBMS2) (AA 173-401) antibody

Details for Product No. ABIN557039, Supplier: Login to see
Antigen
  • zgc:100836
  • RBMS2
  • SCR3
  • 2610315E04Rik
  • Scr3
Epitope
AA 173-401
21
18
6
4
3
3
Reactivity
Human
40
5
5
1
Host
Rabbit
31
9
Clonality
Polyclonal
Conjugate
Un-conjugated
2
2
2
2
2
2
Application
Western Blotting (WB)
37
25
6
1
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Immunogen Recombinant fragment corresponding to a region within amino acids 173 and 401 of RBMS2
Isotype IgG
Predicted Reactivity Human (100%)
Characteristics Cellular Localization: Nucleus
Purification Purified by antigen-affinity chromatography..
Alternative Name RBMS2 / SCR3 (RBMS2 Antibody Abstract)
Background The protein encoded by this gene is a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. The RBMS proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. This protein was isolated by phenotypic complementation of cdc2 and cdc13 mutants of yeast and is thought to suppress cdc2 and cdc13 mutants through the induction of translation of cdc2. [provided by RefSeq]
Synonyms: FLJ39093 antibody, FLJ40023 antibody, FLJ43262 antibody, SCR3 antibody, RBMS2 antibody, suppressor of CDC2 with RNA-binding motif 3 antibody, "RNA-binding motif, single-stranded-interacting protein 2 antibody", "RNA binding motif, single stranded interacting protein 2 antibody"
Molecular Weight 44 kDa
UniProt Q15434
Pathways
Comment

Positive Controls: Target recombinant protein

Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid multiple freeze-thaw cycles.
Storage -20 °C
Storage Comment Keep as concentrated solution. Aliquot and store at -20°C or below.
Product cited in: Partanen, Dumont: "Functions of Tie1 and Tie2 receptor tyrosine kinases in vascular development." in: Current topics in microbiology and immunology, Vol. 237, Issue 4, pp. 159-72, 1999 (PubMed).

Dumont, Gradwohl, Fong et al.: "Dominant-negative and targeted null mutations in the endothelial receptor tyrosine kinase, tek, reveal a critical role in vasculogenesis of the embryo." in: Genes & development, Vol. 8, Issue 16, pp. 1897-909, 1994 (PubMed).