ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 10 (ABCB10) (AA 487-726) antibody

Details for Product No. ABIN557383
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Antigen
Synonyms GB10581, ABCB10, si:dkey-162b3.3, EST20237, M-ABC2, MTABC2, Abc-me, Abcb12
Epitope
AA 487-726
(11), (6), (4), (3), (2), (2), (1), (1), (1), (1)
Reactivity
Human
(30), (7), (6)
Host
Rabbit
(29), (5)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(29), (21), (11), (1)
Pubmed 5 references available
Quantity 0.1 mL
Shipping to United States (Change)
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Catalog No. ABIN557383
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Immunogen Recombinant fragment corresponding to a region within amino acids 487 and 726 of ABCB10
Isotype IgG
Cross-Reactivity Mouse (Murine)
Predicted Reactivity Rat (88%)
Characteristics Cellular Localization: Mitochondrion inner membrane
Purification Purified by antigen-affinity chromatography..
Alternative Name ABCB10
Background The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The function of this mitochondrial protein is unknown. [provided by RefSeq]
Synonyms: EST20237 antibody, M-ABC2 antibody, MTABC2 antibody, ABCB10 antibody, "ATP-binding cassette sub-family B member 10, mitochondrial antibody", mitochondrial ATP-binding cassette 2 antibody, ATP-binding cassette transporter 10 antibody, ABC transporter 10 protein antibody, "ATP-binding cassette, sub-family B (MDR/TAP), member 10 antibody"
Molecular Weight 79 kDa
UniProt Q9NRK6
Comment

Positive Controls: Raji , BCL-1

Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid multiple freeze-thaw cycles.
Storage -20 °C
Storage Comment Keep as concentrated solution. Aliquot and store at -20°C or below.
Product cited in: DiDonato, Hayakawa, Rothwarf et al.: "A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB." in: Nature, Vol. 388, Issue 6642, pp. 548-54, 1997 (PubMed).

Mercurio, Zhu, Murray et al.: "IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation." in: Science (New York, N.Y.), Vol. 278, Issue 5339, pp. 860-6, 1997 (PubMed).

Nakano, Shindo, Sakon et al.: "Differential regulation of IkappaB kinase alpha and beta by two upstream kinases, NF-kappaB-inducing kinase and mitogen-activated protein kinase/ERK kinase kinase-1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, Issue 7, pp. 3537-42, 1998 (PubMed).

Ling, Cao, Goeddel: "NF-kappaB-inducing kinase activates IKK-alpha by phosphorylation of Ser-176." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, Issue 7, pp. 3792-7, 1998 (PubMed).

Rothwarf, Zandi, Natoli et al.: "IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex." in: Nature, Vol. 395, Issue 6699, pp. 297-300, 1998 (PubMed).

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