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3-Ketodihydrosphingosine Reductase (KDSR) (AA 65-296) antibody

Details for Product No. ABIN558203
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Antigen
Synonyms fvt1, zgc:55947, FVT1, DHSR, SDR35C1, 6330410P18Rik, 9430079B08Rik, Fvt1
Epitope
AA 65-296
(8), (1), (1), (1)
Reactivity
Human
(28), (15), (15), (12), (12), (12)
Host
Rabbit
(17), (11)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(19), (13), (10), (3), (3)
Pubmed 1 reference available
Quantity 0.1 mL
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Catalog No. ABIN558203
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Immunogen Recombinant fragment corresponding to a region within amino acids 65 and 296 of FVT1
Isotype IgG
Predicted Reactivity Mouse (92%), Rat (92%), Xenopus laevis (81%), Bovine (91%), Xenopus tropicalis (81%)
Purification Purified by antigen-affinity chromatography..
Alternative Name KDS reductase
Background The protein encoded by this gene catalyzes the reduction of 3-ketodihydrosphingosine to dihydrosphingosine. The putative active site residues of the encoded protein are found on the cytosolic side of the endoplasmic reticulum membrane. A chromosomal rearrangement involving this gene is a cause of follicular lymphoma, also known as type II chronic lymphatic leukemia. The mutation of a conserved residue in the bovine ortholog causes spinal muscular atrophy. [provided by RefSeq]
Synonyms: DHSR antibody, FLJ36555 antibody, FLJ92680 antibody, FVT1 antibody, SDR35C1 antibody, KDSR antibody, "short chain dehydrogenase/reductase family 35C, member 1 antibody", 3-dehydrosphinganine reductase antibody, KDS reductase antibody, FVT-1 antibody, follicular lymphoma variant translocation 1 antibody, follicular variant translocation protein 1 antibody, 3-ketodihydrosphingosine reductase antibody
Molecular Weight 36 kDa
UniProt Q06136
Comment

Positive Controls: 293T , A431 , Jurkat , Raji

Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid multiple freeze-thaw cycles.
Storage -20 °C
Storage Comment Keep as concentrated solution. Aliquot and store at -20°C or below.
Product cited in: Reynolds, Roczniak-Ferguson: "Emerging roles for p120-catenin in cell adhesion and cancer." in: Oncogene, Vol. 23, Issue 48, pp. 7947-56, 2004 (PubMed).

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