Vacuolar Protein Sorting 41 Homolog (S. Cerevisiae) (VPS41) (AA 226-461) antibody

Details for Product No. ABIN558241
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Antigen
Synonyms AI317346, Vam2, mVam2, HVPS41, HVSP41, hVps41p, RGD1560511, ATVAM2, ATVPS41, T23G18.5, T23G18_5, VACUOLAR PROTEIN SORTING 41, VAM2, ZIGZAG SUPPRESSOR 2, ZIP2, vacuolar protein sorting 41
Epitope
AA 226-461
(5), (2), (1), (1)
Reactivity
Human
(13), (3), (2), (2), (2)
Host
Rabbit
(7), (6), (1)
Clonality
Polyclonal
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(9), (9), (3), (2)
Pubmed 5 references available
Quantity 0.1 mL
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Catalog No. ABIN558241
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Immunogen Recombinant fragment corresponding to a region within amino acids 226 and 461 of VPS41
Isotype IgG
Predicted Reactivity Mouse (94%), Chicken (89%), Rat (93%), Bovine (98%)
Purification Purified by antigen-affinity chromatography..
Alternative Name VPS41
Background Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human ortholog of yeast Vps41 protein which is also conserved in Drosophila, tomato, and Arabidopsis. Expression studies in yeast and human indicate that this protein may be involved in the formation and fusion of transport vesicles from the Golgi. Several transcript variants encoding different isoforms have been described for this gene, however, the full-length nature of not all is known. [provided by RefSeq]
Synonyms: HVPS41 antibody, HVSP41 antibody, hVps41p antibody, VPS41 antibody, S53 antibody, vacuolar protein sorting-associated protein 41 homolog antibody, vacuolar assembly protein 41 antibody, vacuolar protein sorting 41 homolog (S. cerevisiae) antibody
Molecular Weight 99 kDa
UniProt P49754
Research Area Signaling
Comment

Positive Controls: NT2D1 , U87-MG , MCF-7

Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid multiple freeze-thaw cycles.
Storage -20 °C
Storage Comment Keep as concentrated solution. Aliquot and store at -20°C or below.
Product cited in: Quelle, Shimoda, Thierfelder et al.: "Cloning of murine Stat6 and human Stat6, Stat proteins that are tyrosine phosphorylated in responses to IL-4 and IL-3 but are not required for mitogenesis." in: Molecular and cellular biology, Vol. 15, Issue 6, pp. 3336-43, 1995 (PubMed).

Hou, Schindler, Henzel et al.: "An interleukin-4-induced transcription factor: IL-4 Stat." in: Science (New York, N.Y.), Vol. 265, Issue 5179, pp. 1701-6, 1994 (PubMed).

Mikita, Campbell, Wu et al.: "Requirements for interleukin-4-induced gene expression and functional characterization of Stat6." in: Molecular and cellular biology, Vol. 16, Issue 10, pp. 5811-20, 1996 (PubMed).

Dent, Hu-Li, Paul et al.: "T helper type 2 inflammatory disease in the absence of interleukin 4 and transcription factor STAT6." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, Issue 23, pp. 13823-8, 1998 (PubMed).

Bromberg, Darnell: "The role of STATs in transcriptional control and their impact on cellular function." in: Oncogene, Vol. 19, Issue 21, pp. 2468-73, 2000 (PubMed).

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