Transmembrane Protease, serine 4 (TMPRSS4) (Ser4) antibody

Details for Product No. ABIN559050
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Antigen
Synonyms tmprss4, zgc:152909, CAPH2, MT-SP2, TMPRSS3, mCAP2
Epitope
Ser4
(14), (5), (2), (1), (1)
Reactivity
Human
(39), (16), (15), (12)
Host
Goat
(30), (9), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
ELISA, Western Blotting (WB)
(21), (12), (10), (10), (9), (3), (1)
Pubmed 10 references available
Quantity 0.1 mg
Shipping to United States (Change)
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Catalog No. ABIN559050
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Immunogen HCFRKHTDVFNWK
Isotype IgG
Specificity This antibody is specific for TMPRSS4 (aa245-57).
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide..
Alternative Name TMPRSS4
Background This gene encodes a member of the serine protease family. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified as a gene overexpressed in pancreatic carcinoma. The encoded protein is membrane bound with a N-terminal anchor sequence and a glycosylated extracellular region containing the serine protease domain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Synonyms: transmembrane serine protease3, membranetype serine protease2, transmembrane protease, serine 4, TMPRSS3, MT-SP2, type II membrane serine protease, membrane-type serine protease 2, MTSP2, TMPRSS4 (aa24557), membranetype serine protease 2, transmembrane protease, serine4, transmembrane serine protease 3, MT SP2
Molecular Weight 48.2 kDa, 47.6 kDa
Comment

Positive Controls: The peptide used to product this antibody is available for purchase (Catalog Number:GTX47593-PEP).

Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Minimize freezing and thawing.
Storage -20 °C
Storage Comment Aliquot and store at -20°C.
Product cited in: Lawrence, Springer: "Leukocytes roll on a selectin at physiologic flow rates: distinction from and prerequisite for adhesion through integrins." in: Cell, Vol. 65, Issue 5, pp. 859-73, 1991 (PubMed).

Polley, Phillips, Wayner et al.: "CD62 and endothelial cell-leukocyte adhesion molecule 1 (ELAM-1) recognize the same carbohydrate ligand, sialyl-Lewis x." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 88, Issue 14, pp. 6224-8, 1991 (PubMed).

Picker, Warnock, Burns et al.: "The neutrophil selectin LECAM-1 presents carbohydrate ligands to the vascular selectins ELAM-1 and GMP-140." in: Cell, Vol. 66, Issue 5, pp. 921-33, 1991 (PubMed).

Bevilacqua, Butcher, Furie et al.: "Selectins: a family of adhesion receptors." in: Cell, Vol. 67, Issue 2, pp. 233, 1991 (PubMed).

Cohn, Melhus, Page et al.: "CFTR: development of high- affinity antibodies and localization in sweat gland." in: Biochemical and biophysical research communications, Vol. 181, Issue 1, pp. 36-43, 1992 (PubMed).

Smith, Kishimoto, Abbassi et al.: "Chemotactic factors regulate lectin adhesion molecule 1 (LECAM-1)-dependent neutrophil adhesion to cytokine-stimulated endothelial cells in vitro." in: The Journal of clinical investigation, Vol. 87, Issue 2, pp. 609-18, 1991 (PubMed).

Jutila, Rott, Berg et al.: "Function and regulation of the neutrophil MEL-14 antigen in vivo: comparison with LFA-1 and MAC-1." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 143, Issue 10, pp. 3318-24, 1989 (PubMed).

Kanof, Strober, James: "Induction of CD4 suppressor T cells with anti-Leu-8 antibody." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 139, Issue 1, pp. 49-54, 1987 (PubMed).

Michie, Garcia, Strickler et al.: "Expression of the Leu-8 antigen by B-cell lymphomas." in: American journal of clinical pathology, Vol. 88, Issue 4, pp. 486-90, 1987 (PubMed).

Lewinsohn, Bargatze, Butcher: "Leukocyte-endothelial cell recognition: evidence of a common molecular mechanism shared by neutrophils, lymphocytes, and other leukocytes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 138, Issue 12, pp. 4313-21, 1987 (PubMed).

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