CHMP3 antibody (Internal Region)

Catalog No. ABIN559706

Product Details anti-CHMP3 Antibody

Target: CHMP3 (Charged Multivesicular Body Protein 3 (CHMP3))

Binding Specificity: Internal Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHMP3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Specificity: Reacts with human 25 kDa hVps24

Cross-Reactivity: Mouse (Murine), Rat (Rattus)

Cross-Reactivity (Details): May cross-react with protein from mouse, rat and other species due to sequence homology.

Purification: Antiserum

Immunogen: Synthetic peptide derived from internal domain of human Vps24 protein

Isotype: IgG

Application Details

Application Notes:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
IHC1:200 - 1:2000 WB1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Must be reconstituted in distilled water.

Storage: 4 °C/-20 °C

Storage Comment: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Expiry Date: 24 months

Target Details for CHMP3

Target: CHMP3 (Charged Multivesicular Body Protein 3 (CHMP3))

Alternative Name: Charged Multivesicular Body Protein 3 (CHMP3 Products)

Synonyms: CG9779 antibody, Dmel\\CG9779 antibody, Vps24 antibody, dvps24 antibody, vps24 antibody, VPS24 antibody, CHMP3 antibody, GB15107 antibody, wu:fb47g01 antibody, zgc:76972 antibody, NEDF antibody, 25.1 antibody, 4921505F14Rik antibody, 9130011K15Rik antibody, CGI-49 antibody, D6Ertd286e antibody, Vacuolar protein sorting 24 antibody, charged multivesicular body protein 3 antibody, SNF7 family protein antibody, hypothetical protein antibody, neuroendocrine differentiation factor, putative antibody, charged multivesicular body protein 3 S homeolog antibody, Vps24 antibody, chmp3 antibody, VPS24.2 antibody, CpipJ_CPIJ004098 antibody, PGTG_02107 antibody, LOC5569267 antibody, Smp_032150 antibody, CHMP3 antibody, LOC410607 antibody, Chmp3 antibody, chmp3.S antibody

Background: Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids.

Gene ID: 51652

UniProt: Q9Y3E7