Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 1-100), (partial) antibody

Details for Product No. ABIN559798
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Antigen
Synonyms
BEST:LD21673, CG17685, CG17696, CG17718, CG40411, D.PARP, Dm.pARTa, Dmel\\CG40411, LD21673.3prime, PARP, PARP-1, PARP1, dPARP, parp, ADPRT, ADPRT 1, ADPRT1, ARTD1, PPOL, pADPRT-1, Adprt, Parp-1, adprt ... show more
BEST:LD21673, CG17685, CG17696, CG17718, CG40411, D.PARP, Dm.pARTa, Dmel\\CG40411, LD21673.3prime, PARP, PARP-1, PARP1, dPARP, parp, ADPRT, ADPRT 1, ADPRT1, ARTD1, PPOL, pADPRT-1, Adprt, Parp-1, adprt1, padprt-1, ppol, 5830444G22Rik, AI893648, Adprp, Adprt1, C80510, parp-1, sPARP-1 show less
Epitope
AA 1-100, partial
(67), (17), (16), (15), (15), (15), (15), (15), (15), (15), (15), (14), (14), (13), (12), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (5), (4), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(310), (50), (50), (13), (4), (4), (4), (3), (3), (1), (1), (1), (1), (1)
Host
Mouse
(328), (32), (1)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(25), (25), (25), (25), (25), (23)
Application
Western Blotting (WB), Immunofluorescence (IF), ELISA
(199), (175), (148), (46), (42), (39), (36), (30), (26), (19), (13), (9), (6), (3), (2), (1), (1), (1), (1)
Pubmed 6 references available
Quantity 100 μg
Shipping to United States ( )
Availability Will be delivered in 11 to 12 Business Days
Request Want additional data for this product?

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Immunogen PARP1 (AAH37545, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 kDa.
Immunogen sequence: MAESSDKLYR VEYAKSGRAS CKKCSESIPK DSLRMAIMVQ SPMFDGKVPH WYHFSCFWKV GHSIRHPDVE VDGFSELRWD DQQKVKKTAE AGGVTGKGQD
Clone 3G4
Isotype IgG2a kappa
Alternative Name PARP1 (PARP1 Antibody Abstract)
Background Gene: poly (ADP-ribose) polymerase 1
Synonyms: ADPRT, ADPRT1, PARP, PARP-1, PPOL, pADPRT-1
Gene ID 142
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Buffer In 1x PBS, pH 7.4
Handling Advice Aliquot to avoid repeated freezing and thawing.
Storage -20
Storage Comment Store at -20
Supplier Images
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 1-100), (partial) antibody Immunofluorescence of monoclonal antibody to PARP1 on HeLa cell. (antibody concentrat...
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 1-100), (partial) antibody (2) PARP1 monoclonal antibody (M01), clone 3G4 Western Blot analysis of PARP1 expression ...
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 1-100), (partial) antibody (3) Detection limit for recombinant GST tagged PARP1 is approximately 0.1 ng/mL as a capt...
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 1-100), (partial) antibody (4) Western Blot detection against Immunogen (36.63 KDa) .
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 1-100), (partial) antibody (5) Immunofluorescence of monoclonal antibody to PARP1 on HeLa cell. (antibody concentrat...
Product cited in: Shen, Oswald, Phelps et al.: "Regulation of FANCD2 by the mTOR pathway contributes to the resistance of cancer cells to DNA double-strand breaks." in: Cancer research, Vol. 73, Issue 11, pp. 3393-401, 2013 (PubMed).

Crawford, Yang, Mattaini et al.: "The metastasis efficiency modifier ribosomal RNA processing 1 homolog B (RRP1B) is a chromatin-associated factor." in: The Journal of biological chemistry, Vol. 284, Issue 42, pp. 28660-73, 2009 (PubMed).

Background publications Faraoni, Compagnone, Lavorgna et al.: "BRCA1, PARP1 and γH2AX in acute myeloid leukemia: Role as biomarkers of response to the PARP inhibitor olaparib." in: Biochimica et biophysica acta, Vol. 1852, Issue 3, pp. 462-72, 2015 (PubMed).

Nicolae, Aho, Vlahos et al.: "The ADP-ribosyltransferase PARP10/ARTD10 interacts with proliferating cell nuclear antigen (PCNA) and is required for DNA damage tolerance." in: The Journal of biological chemistry, Vol. 289, Issue 19, pp. 13627-37, 2014 (PubMed).

Pines, Vrouwe, Marteijn et al.: "PARP1 promotes nucleotide excision repair through DDB2 stabilization and recruitment of ALC1." in: The Journal of cell biology, Vol. 199, Issue 2, pp. 235-49, 2012 (PubMed).

Luijsterburg, Lindh, Acs et al.: "DDB2 promotes chromatin decondensation at UV-induced DNA damage." in: The Journal of cell biology, Vol. 197, Issue 2, pp. 267-81, 2012 (PubMed).

Validation Images
Catalog No. ABIN559798
330.00 $
Plus shipping costs $45.00 and $22.00 dry ice
Quantity
Price
100 μg
330.00 $

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