AGT antibody (AA 376-485)

Catalog No. ABIN559812

Product Details anti-AGT Antibody

Target: AGT (Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT))

Binding Specificity: AA 376-485

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This AGT antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: Mouse monoclonal antibody raised against a partial recombinant AGT.

Sequence: TIHLTMPQLV LQGSYDLQDL LAQAELPAIL HTELNLQKLS NDRIRVGEVL NSIFFELEAD EREPTESTQQ LNKPEVLEVT LNRPFLFAVY DQSATALHFL GRVANPLSTA

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: AGT (AAH11519, 376 a.a. ~ 485 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 1A10

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-AGT antibody (ABIN559812)

Jain, Vinukonda, Fiering, Kumar: "A haplotype of human angiotensinogen gene containing -217A increases blood pressure in transgenic mice compared with -217G." in: American journal of physiology. Regulatory, integrative and comparative physiology, Vol. 295, Issue 6, pp. R1849-57, (2008) (PubMed).

Jain, Li, Patil, Kumar: "HNF-1alpha plays an important role in IL-6-induced expression of the human angiotensinogen gene." in: American journal of physiology. Cell physiology, Vol. 293, Issue 1, pp. C401-10, (2007) (PubMed).

Target Details for AGT

Target: AGT (Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT))

Alternative Name: AGT (AGT Products)

Synonyms: ANHU antibody, SERPINA8 antibody, AI265500 antibody, AngI antibody, AngII antibody, Aogen antibody, Serpina8 antibody, ANRT antibody, Ang antibody, PAT antibody, wu:fb62f06 antibody, wu:fj87b02 antibody, zgc:111892 antibody, AGT antibody, angt antibody, ANGT antibody, angiotensinogen antibody, angiotensinogen (serpin peptidase inhibitor, clade A, member 8) antibody, AGT antibody, Agt antibody, agt antibody

Background: Full Gene Name: angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
Synonyms: ANHU,FLJ92595,FLJ97926,SERPINA8

Gene ID: 183

Pathways: JAK-STAT Signaling, ACE Inhibitor Pathway, EGFR Signaling Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Regulation of Lipid Metabolism by PPARalpha, Protein targeting to Nucleus, Feeding Behaviour, Monocarboxylic Acid Catabolic Process, Dicarboxylic Acid Transport, Positive Regulation of Response to DNA Damage Stimulus, Regulation of long-term Neuronal Synaptic Plasticity