Chloride Channel 2 (CLCN2) (AA 38-387), (full length) antibody

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Antigen
Synonyms CLCN2, CLC2, LOC100150892, AL118368, ClC-2, Clc2, nmf240, CLC-2, CIC-2, ECA2, ECA3, EGI11, EGI3, EGMA, EJM6, EJM8, clC-2
Epitope
AA 38-387, full length
(17), (16), (14), (5), (3), (2), (2), (1), (1), (1)
Reactivity
Human
(55), (16), (14), (3), (3), (3), (1), (1)
Host
Mouse
(34), (19), (4)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(3), (3), (3), (3), (3), (3), (1)
Application
ELISA, RNA Interference (RNAi), Western Blotting (WB)
(43), (34), (7), (5), (2), (1), (1), (1), (1)
Pubmed 4 references available
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Quantity 100 μg
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Immunogen CLCN2 (AAH21578.1, 38 a.a. ~ 387 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Immunogen sequence: TVSTAVIVFE LTGQIAHILP VMIVVILANA VAQSLQPSLY DSIIRIKKLP YLPELGWGRH QQYRVRVEDI MVRDVPHVAL SCTFRDLRLA LHRTKGRMLA LVESPESMIL LGSIERSQVV ALLGAQLSPA RRRQHMQERR ATQTSPLSDQ EGPPTPEASV CFQVNTEDSA FPAARGETHK PLKPALKRGP SVTRNLGESP TGSAESAGIA LRSLFCGSPP PEAASEKLES CEKRKLKRVR ISLASDADLE GEMSPEETHT IFSLLGVDHA YVTSIGRLIG IVTLKELRKA IEGSVTAQGV KVRPPLASFR DSATSSSDTE TTEVHALWGP HSRHGLPREG SPSDSDDKCQ
Clone 3E1
Isotype IgG2a kappa
Cross-Reactivity Human
Alternative Name CLCN2 (CLCN2 Antibody Abstract)
Background Gene: chloride channel 2
Synonyms: CIC-2, CLC2, ECA3, EGI3, EGMA
Gene ID 1181
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Buffer In 1x PBS, pH 7.4
Handling Advice Aliquot to avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store at -20 °C or lower. Aliquot to avoid repeated freezing and thawing.
Supplier Images
Western Blotting (WB) image for anti-Chloride Channel 2 (CLCN2) (AA 38-387), (full length) antibody (ABIN560397) CLCN2 monoclonal antibody (M01), clone 3E1 Western Blot analysis of CLCN2 expression ...
Western Blotting (WB) image for anti-Chloride Channel 2 (CLCN2) (AA 38-387), (full length) antibody (ABIN560397) Western blot analysis of CLCN2 over-expressed 293 cell line, cotransfected with CLCN2...
Western Blotting (WB) image for anti-Chloride Channel 2 (CLCN2) (AA 38-387), (full length) antibody (ABIN560397) Western Blot analysis of CLCN2 expression in transfected 293T cell line by CLCN2 mono...
Image no. 4 for anti-Chloride Channel 2 (CLCN2) (AA 38-387), (full length) antibody (ABIN560397) Western Blot detection against Immunogen (64.24 KDa) .
ELISA image for anti-Chloride Channel 2 (CLCN2) (AA 38-387), (full length) antibody (ABIN560397) Detection limit for recombinant GST tagged CLCN2 is 0.3 ng/ml as a capture antibody.
Product cited in: Datta, Dudek, Tao et al.: "Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery." in: Cell, Vol. 91, Issue 2, pp. 231-41, 1997 (PubMed).

Background publications Kandel, Hay: "The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB." in: Experimental cell research, Vol. 253, Issue 1, pp. 210-29, 1999 (PubMed).

Cantley, Neel: "New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 8, pp. 4240-5, 1999 (PubMed).

Alessi, Andjelkovic, Caudwell et al.: "Mechanism of activation of protein kinase B by insulin and IGF-1." in: The EMBO journal, Vol. 15, Issue 23, pp. 6541-51, 1997 (PubMed).

Catalog No. ABIN560397
$430.00
Plus shipping costs $45.00 and $21.00 dry ice

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