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CTNS antibody (AA 1-100)

CTNS Reactivity: Human WB, ELISA Host: Mouse Monoclonal 5G6 unconjugated
Catalog No. ABIN560527
  • Target See all CTNS Antibodies
    CTNS (Cystinosis, Nephropathic (CTNS))
    Binding Specificity
    • 8
    • 7
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 1-100
    Reactivity
    • 25
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 23
    • 2
    Mouse
    Clonality
    • 24
    • 1
    Monoclonal
    Conjugate
    • 15
    • 2
    • 2
    • 2
    • 2
    • 2
    This CTNS antibody is un-conjugated
    Application
    • 23
    • 17
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Purpose
    Mouse monoclonal antibody raised against a partial recombinant CTNS.
    Sequence
    MIRNWLTIFI LFPLKLVEKC ESSVSLTVPP VVKLENGSST NVSLTLRPPL NATLVITFEI TFRSKNITIL ELPDEVVVPP GVTNSSFQVT SQNVGQLTVY
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Antibody Reactive Against Recombinant Protein.
    Immunogen
    CTNS (NP_004928, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    Clone
    5G6
    Isotype
    IgG2a
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    In 1x PBS, pH 7.4
    Handling Advice
    Aliquot to avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • McEvoy, Sumayao, Slattery, McMorrow, Newsholme: "Cystine accumulation attenuates insulin release from the pancreatic β-cell due to elevated oxidative stress and decreased ATP levels." in: The Journal of physiology, Vol. 593, Issue 23, pp. 5167-82, (2015) (PubMed).

    Bellomo, Corallini, Pastore, Palma, Laurenzi, Emma, Taranta: "Modulation of CTNS gene expression by intracellular thiols." in: Free radical biology & medicine, Vol. 48, Issue 7, pp. 865-72, (2010) (PubMed).

  • Target
    CTNS (Cystinosis, Nephropathic (CTNS))
    Alternative Name
    CTNS (CTNS Products)
    Synonyms
    CTNS-LSB antibody, PQLC4 antibody, AI195360 antibody, AW049661 antibody, zgc:110194 antibody, CTNS antibody, cystinosin, lysosomal cystine transporter antibody, cystinosis, nephropathic antibody, cystinosin, lysosomal cystine transporter L homeolog antibody, CTNS antibody, Ctns antibody, ctns antibody, ctns.L antibody
    Background
    Full Gene Name: cystinosis, nephropathic
    Synonyms: CTNS-LSB,PQLC4
    Gene ID
    1497
    NCBI Accession
    NM_004937
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