Product cited in:
Thompson, Bhansali, Diebold et al.: "DYRK1A controls the transition from proliferation to quiescence during lymphoid development by destabilizing Cyclin D3." in: The Journal of experimental medicine, Vol. 212, Issue 6, pp. 953-70, 2015 (PubMed).
García-Cerro, Martínez, Vidal et al.: "Overexpression of Dyrk1A is implicated in several cognitive, electrophysiological and neuromorphological alterations found in a mouse model of Down syndrome." in: PLoS ONE, Vol. 9, Issue 9, pp. e106572, 2014 (PubMed).
Janel, Sarazin, Corlier et al.: "Plasma DYRK1A as a novel risk factor for Alzheimer's disease." in: Translational psychiatry, Vol. 4, pp. e425, 2014 (PubMed).
Souchet, Latour, Gu et al.: "Molecular rescue of DYRK1A overexpression in cystathionine beta synthase-deficient mouse brain by enriched environment combined with voluntary exercise." in: Journal of molecular neuroscience : MN, Vol. 55, Issue 2, pp. 318-23, 2015 (PubMed).
Rachdi, Kariyawasam, Guez et al.: "Dyrk1a haploinsufficiency induces diabetes in mice through decreased pancreatic beta cell mass." in: Diabetologia, Vol. 57, Issue 5, pp. 960-9, 2014 (PubMed).
Thomazeau, Lassalle, Iafrati et al.: "Prefrontal deficits in a murine model overexpressing the down syndrome candidate gene dyrk1a." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 34, Issue 4, pp. 1138-47, 2014 (PubMed).
Hibaoui, Grad, Letourneau et al.: "Modelling and rescuing neurodevelopmental defect of Down syndrome using induced pluripotent stem cells from monozygotic twins discordant for trisomy 21." in: EMBO molecular medicine, Vol. 6, Issue 2, pp. 259-77, 2014 (PubMed).
Fant, Durieu, Chicanne et al.: "cdc-like/dual-specificity tyrosine phosphorylation-regulated kinases inhibitor leucettine L41 induces mTOR-dependent autophagy: implication for Alzheimer's disease." in: Molecular pharmacology, Vol. 85, Issue 3, pp. 441-50, 2014 (PubMed).
Pons-Espinal, Martinez de Lagran, Dierssen: "Environmental enrichment rescues DYRK1A activity and hippocampal adult neurogenesis in TgDyrk1A." in: Neurobiology of disease, Vol. 60, pp. 18-31, 2013 (PubMed).
Stefos, Soppa, Dierssen et al.: "NGF upregulates the plasminogen activation inhibitor-1 in neurons via the calcineurin/NFAT pathway and the Down syndrome-related proteins DYRK1A and RCAN1 attenuate this effect." in: PLoS ONE, Vol. 8, Issue 6, pp. e67470, 2013 (PubMed).
Laguna, Barallobre, Marchena et al.: "Triplication of DYRK1A causes retinal structural and functional alterations in Down syndrome." in: Human molecular genetics, Vol. 22, Issue 14, pp. 2775-84, 2013 (PubMed).
Tlili, Jacobs, de Koning et al.: "Hepatocyte-specific Dyrk1a gene transfer rescues plasma apolipoprotein A-I levels and aortic Akt/GSK3 pathways in hyperhomocysteinemic mice." in: Biochimica et biophysica acta, Vol. 1832, Issue 6, pp. 718-28, 2013 (PubMed).
Arque, Casanovas, Dierssen: "Dyrk1A is dynamically expressed on subsets of motor neurons and in the neuromuscular junction: possible role in Down syndrome." in: PLoS ONE, Vol. 8, Issue 1, pp. e54285, 2013 (PubMed).
Altafaj, Martín, Ortiz-Abalia et al.: "Normalization of Dyrk1A expression by AAV2/1-shDyrk1A attenuates hippocampal-dependent defects in the Ts65Dn mouse model of Down syndrome." in: Neurobiology of disease, Vol. 52, pp. 117-27, 2013 (PubMed).
Spellman, Ahmed, Dubach et al.: "Expression of trisomic proteins in Down syndrome model systems." in: Gene, Vol. 512, Issue 2, pp. 219-25, 2012 (PubMed).
Guo, Kesimer, Tolun et al.: "The NAD(+)-dependent protein deacetylase activity of SIRT1 is regulated by its oligomeric status." in: Scientific reports, Vol. 2, pp. 640, 2012 (PubMed).
Abekhoukh, Planque, Ripoll et al.: "Dyrk1A, a serine/threonine kinase, is involved in ERK and Akt activation in the brain of hyperhomocysteinemic mice." in: Molecular neurobiology, Vol. 47, Issue 1, pp. 105-16, 2013 (PubMed).
Planque, Dairou, Noll et al.: "Mice deficient in cystathionine beta synthase display increased Dyrk1A and SAHH activities in brain." in: Journal of molecular neuroscience : MN, Vol. 50, Issue 1, pp. 1-6, 2013 (PubMed).
Malinge, Bliss-Moreau, Kirsammer et al.: "Increased dosage of the chromosome 21 ortholog Dyrk1a promotes megakaryoblastic leukemia in a murine model of Down syndrome." in: The Journal of clinical investigation, Vol. 122, Issue 3, pp. 948-62, 2012 (PubMed).
Lilienthal, Kolanowski, Becker: "Development of a sensitive non-radioactive protein kinase assay and its application for detecting DYRK activity in Xenopus laevis oocytes." in: BMC biochemistry, Vol. 11, pp. 20, 2010 (PubMed).
Scott, Berger, McKean: "The role of atmospheric pressure variation in the development of spontaneous pneumothoraces." in: The American review of respiratory disease, Vol. 139, Issue 3, pp. 659-62, 1989 (PubMed).