FOXC2 antibody (AA 421-501)

Catalog No. ABIN560913

Product Details anti-FOXC2 Antibody

Target: FOXC2 (Forkhead Box C2 (MFH-1, Mesenchyme Forkhead 1) (FOXC2))

Binding Specificity: AA 421-501

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FOXC2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Purpose: Mouse monoclonal antibody raised against a partial recombinant FOXC2.

Sequence: AASWYLNHSG DLNHLPGHTF AAQQQTFPNV REMFNSHRLG IENSTLGESQ VSGNASCQLP YRSTPPLYRH AAPYSYDCTK Y

Cross-Reactivity: Human, Rat

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: FOXC2 (NP_005242.1, 421 a.a. ~ 501 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 2H3

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-FOXC2 antibody (ABIN560913)

Imayama, Yamada, Yanamoto, Naruse, Matsushita, Takahashi, Seki, Fujita, Ikeda, Umeda: "FOXC2 expression is associated with tumor proliferation and invasion potential in oral tongue squamous cell carcinoma." in: Pathology oncology research : POR, Vol. 21, Issue 3, pp. 783-91, (2015) (PubMed).

Yu, Chen, Chen, Cheng, Hsu, Chang, Chen, Jan, Hsiao, Chang, Liu, Jeng, Wu, Huang, Su, Hung, Chien, Chen, Kuo, Su: "MiR-520h-mediated FOXC2 regulation is critical for inhibition of lung cancer progression by resveratrol." in: Oncogene, Vol. 32, Issue 4, pp. 431-43, (2013) (PubMed).

Nishida, Mimori, Yokobori, Sudo, Tanaka, Shibata, Ishii, Doki, Mori: "FOXC2 is a novel prognostic factor in human esophageal squamous cell carcinoma." in: Annals of surgical oncology, Vol. 18, Issue 2, pp. 535-42, (2011) (PubMed).

Target Details for FOXC2

Target: FOXC2 (Forkhead Box C2 (MFH-1, Mesenchyme Forkhead 1) (FOXC2))

Alternative Name: FOXC2 (FOXC2 Products)

Synonyms: FKHL14 antibody, LD antibody, MFH-1 antibody, MFH1 antibody, Fkh14 antibody, Hfhbf3 antibody, Mfh1 antibody, Fkhl14 antibody, FOXC2 antibody, Foxc2 antibody, XFD-4 antibody, fd-4 antibody, fd-4' antibody, fkh7 antibody, foxc2b antibody, foxc2 antibody, forkhead box C2 antibody, forkhead box C2 (MFH-1, mesenchyme forkhead 1) antibody, forkhead box C2 S homeolog antibody, forkhead box C2 L homeolog antibody, forkhead box protein C2 antibody, FOXC2 antibody, Foxc2 antibody, foxc2.S antibody, foxc2.L antibody, LOC100734751 antibody

Background: Full Gene Name: forkhead box C2 (MFH-1, mesenchyme forkhead 1)
Synonyms: FKHL14,LD,MFH-1,MFH1

Gene ID: 2303

NCBI Accession: NM_005251