Filamin A antibody (Filamin A, alpha) (AA 1-838)

Details for Product anti-FLNA Antibody No. ABIN560922, Supplier: Log in to see
Antigen
  • fb98b06
  • wu:fb98b06
  • wu:fd09g03
  • wu:fd49a06
  • flna
  • cb967
  • wu:fd18g06
  • MGC147094
  • CG3937
  • Cher
  • Dmel\\CG3937
  • FLN
  • Fil
  • joy
  • sko
  • ABP-280
  • ABPX
  • CSBS
  • CVD1
  • FLN-A
  • FLN1
  • FMD
  • MNS
  • NHBP
  • OPD
  • OPD1
  • OPD2
  • XLVD
  • XMVD
  • RGD1560614
  • Dilp2
  • F730004A14Rik
  • Fln1
  • filamin-1
  • filamin A, alpha (actin binding protein 280)
  • filamin A, alpha
  • filamin B, like
  • cheerio
  • filamin, alpha
  • flna
  • FLNA
  • flnbl
  • cher
  • Flna
Alternatives
anti-Human Filamin A antibody for ELISA
Epitope
AA 1-838, full length
16
15
15
15
11
5
5
4
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
Reactivity
Human
153
96
95
4
4
3
1
1
1
1
Host
Mouse
128
21
4
Clonality (Clone)
Monoclonal ()
Conjugate
This Filamin A antibody is un-conjugated
6
6
6
4
4
4
4
4
4
4
4
4
4
4
2
2
2
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Proximity Ligation Assay (PLA), ELISA, Western Blotting (WB)
72
53
49
42
39
18
14
10
4
2
1
1
1
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

Immunogen FLNA (AAH14654, 1 a.a. ~ 838 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Immunogen sequence: MPSGKVAQPT ITDNKDGTVT VRYAPSEAGL HEMDIRYDNM HIPGSPLQFY VDYVNCGHVT AYGPGLTHGV VNKPATFTVN TKDAGEGGLS LAIEGPSKAE ISCTDNQDGT CSVSYLPVLP GDYSILVKYN EQHVPGSPFT ARVTGDDSMR MSHLKVGSAA DIPINISETD LSLLTATVVP PSGREEPCLL KRLRNGHVGI SFVPKETGEH LVHVKKNGQH VASSPIPVVI SQSEIGDASR VRVSGQGLHE GHTFEPAEFI IDTRDAGYGG LSLSIEGPSK VDINTEDLED GTCRVTYCPT EPGNYIINIK FADQHVPGSP FSVKVTGEGR VKESITRRRR APSVANVGSH CDLSLKIPEI SIQDMTAQVT SPSGKTHEAE IVEGENHTYC IRFVPAEMGT HTVSVKYKGQ HVPGSPFQFT VGPLGEGGAH KVRAGGPGLE RAEAGVPAEF SIWTREAGAG GLAIAVEGPS KAEISFEDRK DGSCGVAYVV QEPGDYEVSV KFNEEHIPDS PFVVPVASPS GDARRLTVSS LQESGLKVNQ PASFAVSLNG AKGAIDAKVH SPSGALEECY VTEIDQDKYA VRFIPRENGV YLIDVKFNGT HIPGSPFKIR VGEPGHGGDP GLVSAYGAGL EGGVTGNPAE FVVNTSNAGA GALSVTIDGP SKVKMDCQEC PEGYRVTYTP MAPGSYLISI KYGGPYHIGG SPFKAKVTGP RLVSNHSLHE TSSVFVDSLT KATCAPQHGA PGPGPADASK VVAKGLGLSK AYVGQKSSFT VDCSKAGNNM LLVGVHGPRT PCEEILVKHV GSRLYSVSYL LKDKGEYTLV VKWGDEHIPG SPYRVVVP
Clone 4E10-1B2
Isotype IgG1 kappa
Cross-Reactivity Human
Alternative Name FLNA (FLNA Antibody Abstract)
Background Full Gene Name: filamin A, alpha (actin binding protein 280)
Synonyms: ABP-280,ABPX,DKFZp434P031,FLN,FLN1,FMD,MNS,NHBP,OPD,OPD1,OPD2
Gene ID 2316
Pathways Maintenance of Protein Location
Application Notes Optimal working dilution should be determined by the investigator.
Comment

Product Quality tested by: Antibody Reactive Against Recombinant Protein.

Restrictions For Research Use only
Buffer In 1x PBS, pH 7.4
Handling Advice Aliquot to avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store at -20 °C or lower. Aliquot to avoid repeated freezing and thawing.
Supplier Images
Western Blotting (WB) image for anti-Filamin A antibody (Filamin A, alpha) (AA 1-838) (ABIN560922) FLNA monoclonal antibody (M01), clone 4E10-1B2 Western Blot analysis of FLNA expressi...
Immunostaining (ISt) image for anti-Filamin A antibody (Filamin A, alpha) (AA 1-838) (ABIN560922) Immunoperoxidase of monoclonal antibody to FLNA on formalin-fixed paraffin-embedded h...
ELISA image for anti-Filamin A antibody (Filamin A, alpha) (AA 1-838) (ABIN560922) Detection limit for recombinant GST tagged FLNA is approximately 0.03ng/ml as a captu...
Proximity Ligation Assay (PLA) image for anti-Filamin A antibody (Filamin A, alpha) (AA 1-838) (ABIN560922) Proximity Ligation Analysis of protein-protein interactions between GP1BA and FLNA. H...
 image for anti-Filamin A antibody (Filamin A, alpha) (AA 1-838) (ABIN560922) Western Blot detection against Immunogen (117.92 KDa) .
Product cited in: Parrini, Mei, Pisanti, Catarzi, Pucatti, Bianchini, Mascalchi, Bertini, Morrone, Cavaliere, Guerrini: "Familial periventricular nodular heterotopia, epilepsy and Melnick-Needles Syndrome caused by a single FLNA mutation with combined gain-of-function and loss-of-function effects." in: Journal of medical genetics, Vol. 52, Issue 6, pp. 405-12, 2015 (PubMed).

Bézie, Picarda, Tesson, Renaudin, Durand, Ménoret, Mérieau, Chiffoleau, Guillonneau, Caron, Anegon: "Fibrinogen-like protein 2/fibroleukin induces long-term allograft survival in a rat model through regulatory B cells." in: PLoS ONE, Vol. 10, Issue 3, pp. e0119686, 2015 (PubMed).

Peverelli, Giardino, Treppiedi, Vitali, Cambiaghi, Locatelli, Lasio, Spada, Lania, Mantovani: "Filamin A (FLNA) plays an essential role in somatostatin receptor 2 (SST2) signaling and stabilization after agonist stimulation in human and rat somatotroph tumor cells." in: Endocrinology, Vol. 155, Issue 8, pp. 2932-41, 2014 (PubMed).

Oegema, Hulst, Theuns-Valks, van Unen, Schot, Mancini, Schipper, de Wit, Sibbles, de Coo, Nanninga, Hofstra, Halley, Brooks: "Novel no-stop FLNA mutation causes multi-organ involvement in males." in: American journal of medical genetics. Part A, Vol. 161A, Issue 9, pp. 2376-84, 2013 (PubMed).

Sakane, Alamir Mahmoud Abdallah, Nakano, Honda, Kitamura, Imoto, Matsushita, Sasaki: "Junctional Rab13-binding protein (JRAB) regulates cell spreading via filamins." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 18, Issue 9, pp. 810-22, 2013 (PubMed).

Peverelli, Mantovani, Vitali, Elli, Olgiati, Ferrero, Laws, Della Mina, Villa, Beck-Peccoz, Spada, Lania: "Filamin-A is essential for dopamine d2 receptor expression and signaling in tumorous lactotrophs." in: The Journal of clinical endocrinology and metabolism, Vol. 97, Issue 3, pp. 967-77, 2012 (PubMed).

Valente, Logan, Mougou-Zerelli, Lee, Silhavy, Brancati, Iannicelli, Travaglini, Romani, Illi, Adams, Szymanska, Mazzotta, Lee, Tolentino, Swistun, Salpietro, Fede, Gabriel, Russ, Cibulskis, Sougnez et al.: "Mutations in TMEM216 perturb ciliogenesis and cause Joubert, Meckel and related syndromes. ..." in: Nature genetics, Vol. 42, Issue 7, pp. 619-25, 2010 (PubMed).