HSD3B1 antibody (AA 1-373)

Catalog No. ABIN561369

Product Details anti-HSD3B1 Antibody

Target: HSD3B1 (Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 1 (HSD3B1))

Binding Specificity: AA 1-373

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HSD3B1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Mouse monoclonal antibody raised against a full length recombinant HSD3B1.

Sequence: MTGWSCLVTG AGGFLGQRII RLLVKEKELK EIRVLDKAFG PELREEFSKL QNKTKLTVLE GDILDEPFLK RACQDVSVII HTACIIDVFG VTHRESIMNV NVKGTQLLLE ACVQASVPVF IYTSSIEVAG PNSYKEIIQN GHEEEPLENT WPAPYPHSKK LAEKAVLAAN GWNLKNGGTL YTCALRPMYI YGEGSRFLSA SINEALNNNG ILSSVGKFST VNPVYVGNVA WAHILALRAL QDPKKAPSIR GQFYYISDDT PHQSYDNLNY TLSKEFGLRL DSRWSFPLSL MYWIGFLLEI VSFLLRPIYT YRPPFNRHIV TLSNSVFTFS YKKAQRDLAY KPLYSWEEAK QKTVEWVGSL VDRHKENLKS KTQ

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: HSD3B1 (AAH31999.1, 1 a.a. ~ 373 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 3C11-D4

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-HSD3B1 antibody (ABIN561369)

Kubota-Nakayama, Nakamura, Konosu-Fukaya, Azmahani, Ise, Yamazaki, Kitawaki, Felizola, Ono, Omata, Morimoto, Iwama, Satoh, Sasano et al.: "Expression of steroidogenic enzymes and their transcription factors in cortisol-producing adrenocortical adenomas: immunohistochemical analysis and quantitative real-time polymerase chain reaction ..." in: Human pathology, Vol. 54, pp. 165-73, (2016) (PubMed).

Azmahani, Nakamura, Felizola, Ozawa, Ise, Inoue, McNamara, Doi, Okamura, Zouboulis, Aiba, Sasano: "Steroidogenic enzymes, their related transcription factors and nuclear receptors in human sebaceous glands under normal and pathological conditions." in: The Journal of steroid biochemistry and molecular biology, Vol. 144 Pt B, pp. 268-79, (2014) (PubMed).

Mao, Shih: "Advances in the diagnosis of gestational trophoblastic tumors and tumor-like lesions." in: Expert opinion on medical diagnostics, Vol. 3, Issue 4, pp. 371-80, (2013) (PubMed).

Ariel, Boldes, Weintraub, Reinus, Beller, Arbel: "Chorangiocarcinoma: a case report and review of the literature." in: International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists, Vol. 28, Issue 3, pp. 267-71, (2009) (PubMed).

Mao, Kurman, Jeng, Huang, Shih: "HSD3B1 as a novel trophoblast-associated marker that assists in the differential diagnosis of trophoblastic tumors and tumorlike lesions." in: The American journal of surgical pathology, Vol. 32, Issue 2, pp. 236-42, (2008) (PubMed).

Shih: "Trophogram, an immunohistochemistry-based algorithmic approach, in the differential diagnosis of trophoblastic tumors and tumorlike lesions." in: Annals of diagnostic pathology, Vol. 11, Issue 3, pp. 228-34, (2007) (PubMed).

Target Details for HSD3B1

Target: HSD3B1 (Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 1 (HSD3B1))

Alternative Name: HSD3B1 (HSD3B1 Products)

Synonyms: 3BETAHSD antibody, HSD3B antibody, HSDB3 antibody, HSDB3A antibody, I antibody, SDR11E1 antibody, HSD3B1 antibody, MGC131206 antibody, D3Ertd383e antibody, 3B-HSD antibody, 3BHSD antibody, si:rp71-68n21.10 antibody, hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 antibody, 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 antibody, hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 L homeolog antibody, HSD3B1 antibody, LOC469446 antibody, LOC713091 antibody, hsd3b1.L antibody, LOC100451655 antibody, Hsd3b1 antibody, hsd3b1 antibody

Background: Full Gene Name: hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
Synonyms: HSD3B,HSDB3,SDR11E1

Gene ID: 3283

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process, Carbohydrate Homeostasis