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Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) (AA 1-373) antibody

Details for Product No. ABIN561369
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Antigen
Synonyms 11-DH, 11-beta-HSD1, CORTRD2, HDL, HSD11, HSD11B, HSD11L, SDR26C1, hsd11, hsd11b, LRRGT00065, Hsd11b1
Epitope
AA 1-373
(12), (5), (4), (4), (4), (3), (2), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(83), (37), (33), (15), (13), (13), (1), (1), (1), (1)
Host
Mouse
(66), (11), (8), (4)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(6), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1)
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB), ELISA
(55), (32), (20), (15), (14), (6), (5), (5), (3), (2), (2), (2), (1), (1)
Pubmed 4 references available
Quantity 100 µg
Shipping to United States (Change)
Availability Will be delivered in 11 to 12 Business Days
Catalog No. ABIN561369
394.24 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen HSD3B1 (AAH31999.1, 1 a.a. ~ 373 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Immunogen sequence: MTGWSCLVTGAGGFLGQRII RLLVKEKELKEIRVLDKAFG PELREEFSKLQNKTKLTVLE GDILDEPFLKRACQDVSVII HTACIIDVFGVTHRESIMNV NVKGTQLLLEACVQASVPVF IYTSSIEVAGPNSYKEIIQN GHEEEPLENTWPAPYPHSKK LAEKAVLAANGWNLKNGGTL YTCALRPMYIYGEGSRFLSA SINEALNNNGILSSVGKFST VNPVYVGNVAWAHILALRAL QDPKKAPSIRGQFYYISDDT PHQSYDNLNYTLSKEFGLRL DSRWSFPLSLMYWIGFLLEI VSFLLRPIYTYRPPFNRHIV TLSNSVFTFSYKKAQRDLAY KPLYSWEEAKQKTVEWVGSL VDRHKENLKSKTQ
Clone 3C11-D4
Isotype IgG1 kappa
Characteristics Mouse monoclonal antibody raised against a full length recombinant HSD3B1.
Alternative Name 3-beta-HSD1 / HSD3B1
Background Gene: hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
Synonyms: HSD3B, HSDB3, SDR11E1
Gene ID 3283, BC031999
Research Area Cancer, Hormones
Application Notes Application specialization: Cell lysate, Recombinant protein, Transfected lysate
Restrictions For Research Use only
Buffer 1x PBS, pH 7.2
Storage -20 °C
Storage Comment Store at -20 °C or lower. Aliquot to avoid repeated freezing and thawing.
Supplier Images
anti-Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) (AA 1-373) antibody Immunoperoxidase of monoclonal antibody to HSD3B1 on formalin-fixed paraffin-embedded human placenta. [antibody concentration 3 µg/mL]
anti-Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) (AA 1-373) antibody (2) HSD3B1 monoclonal antibody (M01), clone 3C11-D4. Western Blot analysis of HSD3B1 expression in human placenta.
anti-Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) (AA 1-373) antibody (3) Immunohistochemical staining of various tissues with hematoxylin and HSD3B1 antibody under high magnification.[antibody concentration 3 µg/mL]
(a) Stomach
(b) Esophagus
(c) Endometrium
(d) Uterine cervix
(e) Placenta
(f) Ovary, clear cell carcinoma
(g) Hepatocellular carcinoma
(h) Breast cancer
(i) Colon adenocarcinoma
(j and k) Cervical carcinoma
(l, m, and n) Choriocarcinoma
(o) Epithelioid trophoblastic tumor.
anti-Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) (AA 1-373) antibody (4) Western Blot analysis of HSD3B1 expression in transfected 293T cell line by HSD3B1 monoclonal antibody (M01), clone 3C11-D4.

Lane 1: HSD3B1 transfected lysate (Predicted MW: 42.3 kDa).
Lane 2: Non-transfected lysate.
anti-Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) (AA 1-373) antibody (5) Western Blot detection against Immunogen (66.77 kDa) .
Product cited in: Shih: "Trophogram, an immunohistochemistry-based algorithmic approach, in the differential diagnosis of trophoblastic tumors and tumorlike lesions." in: Annals of diagnostic pathology, Vol. 11, Issue 3, pp. 228-34, 2007 (PubMed).

Mao, Kurman, Jeng et al.: "HSD3B1 as a novel trophoblast-associated marker that assists in the differential diagnosis of trophoblastic tumors and tumorlike lesions." in: The American journal of surgical pathology, Vol. 32, Issue 2, pp. 236-42, 2008 (PubMed).

Ariel, Boldes, Weintraub et al.: "Chorangiocarcinoma: a case report and review of the literature." in: International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists, Vol. 28, Issue 3, pp. 267-71, 2009 (PubMed).

Mao, Shih: "Advances in the diagnosis of gestational trophoblastic tumors and tumor-like lesions." in: Expert opinion on medical diagnostics, Vol. 3, Issue 4, pp. 371-80, 2013 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN561369
394.24 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
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