Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) (AA 187-276), (partial) antibody

Details for Product No. ABIN562160
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Antigen
Synonyms 3j828, MGC52849, MGC132353, Pdk, zgc:56209, PDK2, PDHK2, PDKII
Epitope
AA 187-276, partial
(19), (17), (15), (15), (7), (7), (5), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(116), (62), (34), (2), (1)
Host
Mouse
(102), (38)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(10), (10), (9), (8), (8), (8), (1), (1), (1), (1), (1), (1), (1), (1)
Application
ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), RNA Interference (RNAi), Western Blotting (WB)
(126), (81), (55), (25), (19), (12), (10), (6), (3), (2), (2), (2), (1), (1)
Pubmed 4 references available
Quantity 100 μg
Shipping to United States ( )
Availability Will be delivered in 11 to 12 Business Days
Request Want additional data for this product?

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Immunogen PDK2 (AAH05811, 187 a.a. ~ 276 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 kDa.
Immunogen sequence: HIGSIDPNCN VSEVVKDAYD MAKLLCDKYY MASPDLEIQE INAANSKQPI HMVYVPSHLY HMLFELFKNA MRATVESHES SLILPPIKVM
Clone 2G1
Isotype IgG2a kappa
Alternative Name PDK2 (PDK2 Antibody Abstract)
Background Gene: pyruvate dehydrogenase kinase, isozyme 2
Synonyms: PDHK2
Gene ID 5164
Research Area Cancer, Metabolism
Pathways PI3K-Akt Signaling Pathway
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Buffer In 1x PBS, pH 7.4
Handling Advice Aliquot to avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Supplier Images
anti-Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) (AA 187-276), (partial) antibody PDK2 monoclonal antibody (M01), clone 2G1 Western Blot analysis of PDK2 expression in...
anti-Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) (AA 187-276), (partial) antibody (2) Western blot analysis of PDK2 over-expressed 293 cell line, cotransfected with PDK2 V...
anti-Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) (AA 187-276), (partial) antibody (3) Immunoperoxidase of monoclonal antibody to PDK2 on formalin-fixed paraffin-embedded h...
anti-Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) (AA 187-276), (partial) antibody (4) Detection limit for recombinant GST tagged PDK2 is approximately 0.3 ng/mL as a captu...
anti-Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) (AA 187-276), (partial) antibody (5) Western Blot analysis of PDK2 expression in transfected 293T cell line by PDK2 monocl...
anti-Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) (AA 187-276), (partial) antibody (6) Western Blot detection against Immunogen (35.31 KDa) .
Product cited in: Gannon, Ables, Crawford et al.: "pdx-1 function is specifically required in embryonic beta cells to generate appropriate numbers of endocrine cell types and maintain glucose homeostasis." in: Developmental biology, Vol. 314, Issue 2, pp. 406-17, 2008 (PubMed).

Babu, Deering, Mirmira: "A feat of metabolic proportions: Pdx1 orchestrates islet development and function in the maintenance of glucose homeostasis." in: Molecular genetics and metabolism, Vol. 92, Issue 1-2, pp. 43-55, 2007 (PubMed).

Gu, Dubauskaite, Melton: "Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors." in: Development (Cambridge, England), Vol. 129, Issue 10, pp. 2447-57, 2002 (PubMed).

Ohlsson, Karlsson, Edlund: "IPF1, a homeodomain-containing transactivator of the insulin gene." in: The EMBO journal, Vol. 12, Issue 11, pp. 4251-9, 1993 (PubMed).

Validation Images
Catalog No. ABIN562160
330.00 $
Plus shipping costs $45.00 and $22.00 dry ice
Quantity
Price
100 μg
330.00 $

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