PITX2 antibody (AA 1-324)

Catalog No. ABIN562251

Product Details anti-PITX2 Antibody

Target: PITX2 (Paired-Like Homeodomain 2 (PITX2))

Binding Specificity: AA 1-324

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PITX2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Purpose: Mouse monoclonal antibody raised against a full length recombinant PITX2.

Sequence: MNCMKGPLHL EHRAAGTKLS AVSSSSCHHP QPLAMASVLA PGQPRSLDSS KHRLEVHTIS DTSSPEAAEK DKSQQGKNED VGAEDPSKKK RQRRQRTHFT SQQLQELEAT FQRNRYPDMS TREEIAVWTN LTEARVRVWF KNRRAKWRKR ERNQQAELCK NGFGPQFNGL MQPYDDMYPG YSYNNWAAKG LTSASLSTKS FPFFNSMNVN PLSSQSMFSP PNSISSMSMS SSMVPSAVTG VPGSSLNSLN NLNNLSSPSL NSAVPTPACP YAPPTPPYVY RDTCNSSLAS LRLKAKQHSS FGYASVQNPA SNLSACQYAV DRPV

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: PITX2 (AAH13998, 1 a.a. ~ 324 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 2G6

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-PITX2 antibody (ABIN562251)

Strungaru, Footz, Liu, Berry, Belleau, Semina, Raymond, Walter: "PITX2 is involved in stress response in cultured human trabecular meshwork cells through regulation of SLC13A3." in: Investigative ophthalmology & visual science, Vol. 52, Issue 10, pp. 7625-33, (2011) (PubMed).

Acharya, Lingenfelter, Huang, Gage, Walter: "Human PRKC apoptosis WT1 regulator is a novel PITX2-interacting protein that regulates PITX2 transcriptional activity in ocular cells." in: The Journal of biological chemistry, Vol. 284, Issue 50, pp. 34829-38, (2009) (PubMed).

Target Details for PITX2

Target: PITX2 (Paired-Like Homeodomain 2 (PITX2))

Alternative Name: PITX2 (PITX2 Products)

Synonyms: ARP1 antibody, Brx1 antibody, IDG2 antibody, IGDS antibody, IGDS2 antibody, IHG2 antibody, IRID2 antibody, Otlx2 antibody, PTX2 antibody, RGS antibody, RIEG antibody, RIEG1 antibody, RS antibody, 9430085M16Rik antibody, Brx1a antibody, Brx1b antibody, Munc30 antibody, Pitx2a antibody, Pitx2b antibody, Pitx2c antibody, Pitx2cbeta antibody, Ptx2 antibody, Rieg antibody, pitx2a antibody, pitx2c antibody, zgc:110508 antibody, XPtx2b antibody, xPtx2 antibody, xpitx2 antibody, arp1 antibody, brx1 antibody, idg2 antibody, igds antibody, igds2 antibody, ihg2 antibody, irid2 antibody, otlx2 antibody, pitx2-A antibody, ptx2 antibody, rgs antibody, rieg antibody, rieg1 antibody, pitx-2 antibody, pitx2 antibody, paired like homeodomain 2 antibody, paired-like homeodomain transcription factor 2 antibody, paired-like homeodomain 2 antibody, paired like homeodomain 2 S homeolog antibody, paired like homeodomain 2 L homeolog antibody, PITX2 antibody, Pitx2 antibody, pitx2 antibody, pitx2.S antibody, pitx2.L antibody

Background: Full Gene Name: paired-like homeodomain 2
Synonyms: ARP1,Brx1,IDG2,IGDS,IGDS2,IHG2,IRID2,MGC111022,MGC20144,Otlx2,PTX2,RGS,RIEG,RIEG1,RS

Gene ID: 5308

Pathways: Retinoic Acid Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development