SH3G2 antibody (AA 64-124)

Catalog No. ABIN562863

Product Details anti-SH3G2 Antibody

Target: SH3G2 (Endophilin-A1 (SH3G2))

Binding Specificity: AA 64-124

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SH3G2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Mouse monoclonal antibody raised against a partial recombinant SH3GL2.

Sequence: SRAKLSMINT MSKIRGQEKG PGYPQAEALL AEAMLKFGRE LGDDCNFGPA LGEVGEAMRE L

Cross-Reactivity: Human, Rat

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: SH3GL2 (NP_003017, 64 a.a. ~ 124 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 5A6

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-SH3G2 antibody (ABIN562863)

Dasgupta, Jang, Shao, Mukhopadhyay, Sokhi, Das, Brait, Talbot, Yung, Begum, Westra, Hoque, Yang, Yi, Lam, Gazdar, Fisher, Jen, Sidransky: "SH3GL2 is frequently deleted in non-small cell lung cancer and downregulates tumor growth by modulating EGFR signaling." in: Journal of molecular medicine (Berlin, Germany), Vol. 91, Issue 3, pp. 381-93, (2013) (PubMed).

Target Details for SH3G2

Target: SH3G2 (Endophilin-A1 (SH3G2))

Alternative Name: SH3GL2 (SH3G2 Products)

Synonyms: CNSA2 antibody, EEN-B1 antibody, SH3D2A antibody, SH3P4 antibody, 9530001L19Rik antibody, AI120490 antibody, AW555077 antibody, B930049H17Rik antibody, SH3PA antibody, Sh3d2a antibody, Sh3p4 antibody, SH3 domain containing GRB2 like 2, endophilin A1 antibody, SH3-domain GRB2-like 2 antibody, SH3GL2 antibody, Sh3gl2 antibody

Background: Full Gene Name: SH3-domain GRB2-like 2
Synonyms: CNSA2,EEN-B1,FLJ20276,FLJ25015,SH3D2A,SH3P4

Gene ID: 6456

NCBI Accession: NM_003026

Pathways: Neurotrophin Signaling Pathway, EGFR Downregulation