SMPD2 antibody (AA 1-423)

Catalog No. ABIN562924

Product Details anti-SMPD2 Antibody

Target: SMPD2 (Sphingomyelin phosphodiesterase 2, Neutral Membrane (Neutral Sphingomyelinase) (SMPD2))

Binding Specificity: AA 1-423

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SMPD2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Mouse monoclonal antibody raised against a full length recombinant SMPD2.

Sequence: MKPNFSLRLR IFNLNCWGIP YLSKHRADRM RRLGDFLNQE SFDLALLEEV WSEQDFQYLR QKLSPTYPAA HHFRSGIIGS GLCVFSKHPI QELTQHIYTL NGYPYMIHHG DWFSGKAVGL LVLHLSGMVL NAYVTHLHAE YNRQKDIYLA HRVAQAWELA QFIHHTSKKA DVVLLCGDLN MHPEDLGCCL LKEWTGLHDA YLETRDFKGS EEGNTMVPKN CYVSQQELKP FPFGVRIDYV LYKAVSGFYI SCKSFETTTG FDPHSGTPLS DHEALMATLF VRHSPPQQNP SSTHGPAERS PLMCVLKEAW TELGLGMAQA RWWATFASYV IGLGLLLLAL LCVLAAGGGA GEAAILLWTP SVGLVLWAGA FYLFHVQEVN GLYRAQAELQ HVLGRAREAQ DLGPEPQPAL LLGQQEGDRT KEQ

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: SMPD2 (AAH00038.1, 1 a.a. ~ 423 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 2C9

Isotype: IgG3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-SMPD2 antibody (ABIN562924)

Lee, Tan, Venkatratnam, Tan, Cui, Loh, Griffith, Tannenbaum, Chan: "Dysregulated sphingolipid metabolism in endometriosis." in: The Journal of clinical endocrinology and metabolism, Vol. 99, Issue 10, pp. E1913-21, (2014) (PubMed).

Target Details for SMPD2

Target: SMPD2 (Sphingomyelin phosphodiesterase 2, Neutral Membrane (Neutral Sphingomyelinase) (SMPD2))

Alternative Name: SMPD2 (SMPD2 Products)

Background: Full Gene Name: sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
Synonyms: NSMASE,NSMASE1

Gene ID: 6610

Pathways: Neurotrophin Signaling Pathway