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serine Peptidase Inhibitor, Kazal Type 1 (SPINK1) (AA 24-79), (partial) antibody

Details for Product No. ABIN562978, Supplier: Login to see
Antigen
  • SPINK1
  • Psti
  • Spink3
  • PCTT
  • PSTI
  • TATI
  • TCP
  • Psti-1
  • Spink1
  • Tilp
Epitope
AA 24-79, partial
13
4
4
3
3
2
2
2
1
Reactivity
Human
49
17
4
Host
Mouse
51
10
1
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
2
2
2
2
2
2
2
2
2
2
2
2
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), ELISA, Western Blotting (WB)
33
22
17
11
11
7
3
3
1
1
Supplier
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Immunogen SPINK1 (AAH25790, 24 a.a. ~ 79 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Immunogen sequence: DSLGREAKCY NELNGCTKIY DPVCGTDGNT YPNECVLCFE NRKRQTSILI QKSGPC
Clone 4D4
Isotype IgG2a kappa
Cross-Reactivity Human
Alternative Name SPINK1 (SPINK1 Antibody Abstract)
Background Full Gene Name: serine peptidase inhibitor, Kazal type 1
Synonyms: PCTT,PSTI,Spink3,TATI
Gene ID 6690
Research Area Proteolysis / Ubiquitin
Pathways
Application Notes Optimal working dilution should be determined by the investigator.
Comment

Product Quality tested by: Antibody Reactive Against Recombinant Protein.

Restrictions For Research Use only
Buffer In 1x PBS, pH 7.4
Handling Advice Aliquot to avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store at -20 °C or lower. Aliquot to avoid repeated freezing and thawing.
Supplier Images
Immunostaining (ISt) image for anti-serine Peptidase Inhibitor, Kazal Type 1 (SPINK1) (AA 24-79), (partial) antibody (ABIN562978) Immunoperoxidase of monoclonal antibody to SPINK1 on formalin-fixed paraffin-embedded...
Western Blotting (WB) image for anti-serine Peptidase Inhibitor, Kazal Type 1 (SPINK1) (AA 24-79), (partial) antibody (ABIN562978) SPINK1 monoclonal antibody (M01), clone 4D4. Western Blot analysis of SPINK1 expressi...
Immunoprecipitation (IP) image for anti-serine Peptidase Inhibitor, Kazal Type 1 (SPINK1) (AA 24-79), (partial) antibody (ABIN562978) Immunoprecipitation of SPINK1 transfected lysate using anti-SPINK1 monoclonal antibod...
ELISA image for anti-serine Peptidase Inhibitor, Kazal Type 1 (SPINK1) (AA 24-79), (partial) antibody (ABIN562978) Detection limit for recombinant GST tagged SPINK1 is 0.03 ng/ml as a capture antibody.
 image for anti-serine Peptidase Inhibitor, Kazal Type 1 (SPINK1) (AA 24-79), (partial) antibody (ABIN562978) Western Blot detection against Immunogen (31.9 KDa) .
Product cited in: Zhang, Wang, Hu et al.: "The construction and proliferative effects of a lentiviral vector capable of stably overexpressing SPINK1 gene in human pancreatic cancer AsPC-1 cell line." in: Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2015 (PubMed).

Ateeq, Kunju, Carskadon et al.: "Molecular profiling of ETS and non-ETS aberrations in prostate cancer patients from northern India." in: The Prostate, Vol. 75, Issue 10, pp. 1051-62, 2015 (PubMed).

Palanisamy, Tsodikov, Yan et al.: "Molecular profiling of ETS gene rearrangements in patients with prostate cancer registered in REDEEM clinical trial." in: Urologic oncology, Vol. 33, Issue 3, pp. 108.e5-108.e13, 2015 (PubMed).

Smith, Palanisamy, Zuhlke et al.: "HOXB13 G84E-related familial prostate cancers: a clinical, histologic, and molecular survey." in: The American journal of surgical pathology, Vol. 38, Issue 5, pp. 615-26, 2014 (PubMed).

Bhalla, Kunju, Tomlins et al.: "Novel dual-color immunohistochemical methods for detecting ERG-PTEN and ERG-SPINK1 status in prostate carcinoma." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 26, Issue 6, pp. 835-48, 2013 (PubMed).

Rink, Park, Volkmer et al.: "Loss of SPINK1 expression is associated with unfavorable outcomes in urothelial carcinoma of the bladder after radical cystectomy." in: Urologic oncology, Vol. 31, Issue 8, pp. 1716-24, 2013 (PubMed).

Han, Mehra, Suleman et al.: "Characterization of ETS gene aberrations in select histologic variants of prostate carcinoma." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 22, Issue 9, pp. 1176-85, 2009 (PubMed).

Tomlins, Rhodes, Yu et al.: "The role of SPINK1 in ETS rearrangement-negative prostate cancers. ..." in: Cancer cell, Vol. 13, Issue 6, pp. 519-28, 2008 (PubMed).