Neuregulin 2 antibody (AA 116-215)

Catalog No. ABIN564118

Product Details anti-Neuregulin 2 Antibody

Target: Neuregulin 2 (NRG2)

Binding Specificity: AA 116-215

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Neuregulin 2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: Mouse monoclonal antibody raised against a partial recombinant NRG2.

Sequence: SLKSVQDQAY KAPVVVEGKV QGLVPAGGSS SNSTREPPAS GRVALVKVLD KWPLRSGGLQ REQVISVGSC VPLERNQRYI FFLEPTEQPL VFKTAFAPLD

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: NRG2 (NP_004874, 116 a.a. ~ 215 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 3D2

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-Neuregulin 2 antibody (ABIN564118)

Frogne, Benjaminsen, Sonne-Hansen, Sorensen, Nexo, Laenkholm, Rasmussen, Riese, de Cremoux, Stenvang, Lykkesfeldt: "Activation of ErbB3, EGFR and Erk is essential for growth of human breast cancer cell lines with acquired resistance to fulvestrant." in: Breast cancer research and treatment, Vol. 114, Issue 2, pp. 263-75, (2009) (PubMed).

Target Details for Neuregulin 2

Target: Neuregulin 2 (NRG2)

Alternative Name: NRG2 (NRG2 Products)

Background: Full Gene Name: neuregulin 2
Synonyms: Don-1,HRG2,NTAK

Gene ID: 9542

NCBI Accession: NM_004883

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway