MTSS1 antibody (AA 346-445)

Catalog No. ABIN3013366

Product Details anti-MTSS1 Antibody

Target: MTSS1 (Metastasis Suppressor 1 (MTSS1))

Binding Specificity: AA 346-445

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MTSS1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Mouse monoclonal antibody raised against a partial recombinant MTSS1.

Sequence: GVLPAPPDGP EERGEHSPES PSVGEGPQGV TSMPSSMWSG QASVNPPLPG PKPSIPEEHR QAIPESEAED QEREPPSATV SPGQIPESDP ADLSPRDTPQ

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: MTSS1 (AAH23998, 346 a.a. ~ 445 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 2G9

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-MTSS1 antibody (ABIN3013366)

Mertz, Pathria, Wagner, Saarikangas, Sboner, Romanov, Gschaider, Lenz, Neumann, Schreiner, Nemethova, Glassmann, Lappalainen, Stingl, Small, Fink, Chin, Wagner: "MTSS1 is a metastasis driver in a subset of human melanomas." in: Nature communications, Vol. 5, pp. 3465, (2014) (PubMed).

Xu, Ayub, Liu, Serna, Qiang, Liu, Hernando, Zabludoff, Kurita, Kong, Wei: "Anti-miR182 reduces ovarian cancer burden, invasion, and metastasis: an in vivo study in orthotopic xenografts of nude mice." in: Molecular cancer therapeutics, Vol. 13, Issue 7, pp. 1729-39, (2014) (PubMed).

Xie, Ye, Chen, Wu, Zhang, Yang, Zhang, Jiang: "The impact of Metastasis Suppressor-1, MTSS1, on oesophageal squamous cell carcinoma and its clinical significance." in: Journal of translational medicine, Vol. 9, pp. 95, (2011) (PubMed).

Liu, Wang, Ding, Chen, Yu, Wang: "Downregulation of metastasis suppressor 1(MTSS1) is associated with nodal metastasis and poor outcome in Chinese patients with gastric cancer." in: BMC cancer, Vol. 10, pp. 428, (2010) (PubMed).

Parr, Jiang: "Metastasis suppressor 1 (MTSS1) demonstrates prognostic value and anti-metastatic properties in breast cancer." in: European journal of cancer (Oxford, England : 1990), Vol. 45, Issue 9, pp. 1673-83, (2009) (PubMed).

Target Details for MTSS1

Target: MTSS1 (Metastasis Suppressor 1 (MTSS1))

Alternative Name: MTSS1 (MTSS1 Products)

Background: Gene: metastasis suppressor 1
Synonyms: DKFZp781P2223, FLJ44694, KIAA0429, MIM, MIMA, MIMB

Gene ID: 9788