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USP15 antibody (AA 1-235)

USP15 Reactivity: Human WB, ELISA, IF Host: Mouse Monoclonal 1C10 unconjugated
Catalog No. ABIN564282
  • Target See all USP15 Antibodies
    USP15 (Ubiquitin Specific Peptidase 15 (USP15))
    Binding Specificity
    • 9
    • 8
    • 7
    • 7
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-235
    Reactivity
    • 48
    • 27
    • 8
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 47
    • 1
    Mouse
    Clonality
    • 47
    Monoclonal
    Conjugate
    • 26
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This USP15 antibody is un-conjugated
    Application
    • 36
    • 27
    • 9
    • 8
    • 4
    • 3
    • 2
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    Purpose
    Mouse monoclonal antibody raised against a full length recombinant USP15.
    Sequence
    MAEGGAADLD TQRSDIATLL KTSLRKGDTW YLVDSRWFKQ WKKYVGFDSW DKYQMGDQNV YPGPIDNSGL LKDGDAQSLK EHLIDELDYI LLPTEGWNKL VSWYTLMEGQ EPIARKVVEQ GMFVKHCKVE VYLTELKLCE NGNMNNVVTR RFSKADTIDT IEKEIRKIFS IPDEKETRLW NKYMSNTFEP LNKPDSTIQD AGLYQGQVLV IEQKNEDGTW PRGPSTPKKP LEQSC
    Cross-Reactivity
    Human
    Characteristics
    Antibody Reactive Against Recombinant Protein.
    Immunogen
    USP15 (AAH20688, 1 a.a. ~ 235 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    Clone
    1C10
    Isotype
    IgG1
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    In 1x PBS, pH 7.4
    Handling Advice
    Aliquot to avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Pauli, Chan, Davis, Gableske, Wang, Feister, Gack: "The ubiquitin-specific protease USP15 promotes RIG-I-mediated antiviral signaling by deubiquitylating TRIM25." in: Science signaling, Vol. 7, Issue 307, pp. ra3, (2014) (PubMed).

    García-Caballero, Gadotti, Stemkowski, Weiss, Souza, Hodgkinson, Bladen, Chen, Hamid, Pizzoccaro, Deage, François, Bourinet, Zamponi: "The deubiquitinating enzyme USP5 modulates neuropathic and inflammatory pain by enhancing Cav3.2 channel activity." in: Neuron, Vol. 83, Issue 5, pp. 1144-58, (2014) (PubMed).

    Cornelissen, Haddad, Wauters, Van Humbeeck, Mandemakers, Koentjoro, Sue, Gevaert, De Strooper, Verstreken, Vandenberghe: "The deubiquitinase USP15 antagonizes Parkin-mediated mitochondrial ubiquitination and mitophagy." in: Human molecular genetics, Vol. 23, Issue 19, pp. 5227-42, (2014) (PubMed).

    Fernandez-Sanchez, Sechet, Margottin-Goguet, Rogge, Bianchi: "The human COP9 signalosome protects ubiquitin-conjugating enzyme 3 (UBC3/Cdc34) from beta-transducin repeat-containing protein (betaTrCP)-mediated degradation." in: The Journal of biological chemistry, Vol. 285, Issue 23, pp. 17390-7, (2010) (PubMed).

    Vos, Altreuter, White, Howley: "The ubiquitin-specific peptidase USP15 regulates human papillomavirus type 16 E6 protein stability." in: Journal of virology, Vol. 83, Issue 17, pp. 8885-92, (2009) (PubMed).

    Xu, Takanashi, Oikawa, Tanaka, Nishi, Isaka, Kudo, Kuroda: "USP15 plays an essential role for caspase-3 activation during Paclitaxel-induced apoptosis." in: Biochemical and biophysical research communications, Vol. 388, Issue 2, pp. 366-71, (2009) (PubMed).

    Cayli, Klug, Chapiro, Fröhlich, Krasteva, Orel, Meinhardt: "COP9 signalosome interacts ATP-dependently with p97/valosin-containing protein (VCP) and controls the ubiquitination status of proteins bound to p97/VCP." in: The Journal of biological chemistry, Vol. 284, Issue 50, pp. 34944-53, (2009) (PubMed).

    Miyauchi, Kato, Tokunaga, Iwai: "The COP9/signalosome increases the efficiency of von Hippel-Lindau protein ubiquitin ligase-mediated hypoxia-inducible factor-alpha ubiquitination." in: The Journal of biological chemistry, Vol. 283, Issue 24, pp. 16622-31, (2008) (PubMed).

    Schweitzer, Bozko, Dubiel, Naumann: "CSN controls NF-kappaB by deubiquitinylation of IkappaBalpha." in: The EMBO journal, Vol. 26, Issue 6, pp. 1532-41, (2007) (PubMed).

  • Target
    USP15 (Ubiquitin Specific Peptidase 15 (USP15))
    Alternative Name
    USP15 (USP15 Products)
    Synonyms
    USP15 antibody, UNP antibody, UNPH-2 antibody, UNPH4 antibody, 4921514G19Rik antibody, AI327321 antibody, E430033I05Rik antibody, Gcap18 antibody, mKIAA0529 antibody, Ubp109 antibody, ubiquitin specific peptidase 15 antibody, universal stress protein UspA antibody, ubiquitin carboxyl-terminal hydrolase 15 antibody, USP15 antibody, RR_RS05795 antibody, LOC100090554 antibody, usp15 antibody, Usp15 antibody
    Background
    Full Gene Name: ubiquitin specific peptidase 15
    Synonyms: KIAA0529,MGC131982,MGC149838,MGC74854,UNPH4
    Gene ID
    9958
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