SLC12A6 antibody (AA 1-90)

Catalog No. ABIN564298

Product Details anti-SLC12A6 Antibody

Target: SLC12A6 (Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 6 (SLC12A6))

Binding Specificity: AA 1-90

Reactivity: Human

Host: Mouse

Clonality: Polyclonal

Conjugate: This SLC12A6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: Mouse polyclonal antibody raised against a partial recombinant SLC12A6.

Sequence: MPHFTVTKVE DPEEGAAASI SQEPSLADIK ARIQDSDEPD LSQNSITGEH SQLLDDGHKK ARNAYLNNSN YEEGDEYFDK NLALFEEEMD

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: SLC12A6 (NP_005126, 1 a.a. ~ 90 a.a) partial recombinant protein with GST tag.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 50 % glycerol

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-SLC12A6 antibody (ABIN564298)

Salin-Cantegrel, Shekarabi, Rasheed, Charron, Laganière, Gaudet, Dion, Lapointe, Rouleau: "Potassium-chloride cotransporter 3 interacts with Vav2 to synchronize the cell volume decrease response with cell protrusion dynamics." in: PLoS ONE, Vol. 8, Issue 5, pp. e65294, (2013) (PubMed).

Shekarabi, Moldrich, Rasheed, Salin-Cantegrel, Laganière, Rochefort, Hince, Huot, Gaudet, Kurniawan, Sotocinal, Ritchie, Dion, Mogil, Richards, Rouleau et al.: "Loss of neuronal potassium/chloride cotransporter 3 (KCC3) is responsible for the degenerative phenotype in a conditional mouse model of hereditary motor and sensory neuropathy associated with ..." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 32, Issue 11, pp. 3865-76, (2012) (PubMed).

Salin-Cantegrel, Rivière, Shekarabi, Rasheed, Dacal, Laganière, Gaudet, Rochefort, Lesca, Gaspar, Dion, Lapointe, Rouleau: "Transit defect of potassium-chloride Co-transporter 3 is a major pathogenic mechanism in hereditary motor and sensory neuropathy with agenesis of the corpus callosum." in: The Journal of biological chemistry, Vol. 286, Issue 32, pp. 28456-65, (2011) (PubMed).

Salin-Cantegrel, Shekarabi, Holbert, Dion, Rochefort, Laganière, Dacal, Hince, Karemera, Gaspar, Lapointe, Rouleau: "HMSN/ACC truncation mutations disrupt brain-type creatine kinase-dependant activation of K+/Cl- co-transporter 3." in: Human molecular genetics, Vol. 17, Issue 17, pp. 2703-11, (2008) (PubMed).

Target Details for SLC12A6

Target: SLC12A6 (Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 6 (SLC12A6))

Alternative Name: SLC12A6 (SLC12A6 Products)

Synonyms: Kcc3 antibody, ACCPN antibody, KCC3 antibody, KCC3A antibody, KCC3B antibody, 9530023I19Rik antibody, gaxp antibody, solute carrier family 12, member 6 antibody, solute carrier family 12 member 6 antibody, Slc12a6 antibody, SLC12A6 antibody

Background: Full Gene Name: solute carrier family 12 (potassium/chloride transporters), member 6
Synonyms: ACCPN,DKFZp434D2135,KCC3,KCC3A,KCC3B

Gene ID: 9990

NCBI Accession: NM_005135