TAR DNA Binding Protein (TARDBP) (AA 1-260), (full length) antibody

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Antigen
Synonyms TARDBP, TDP43, DKFZp459I2127, tardbp, ALS10, TDP-43, 1190002A23Rik, C85084, Tdp43, wu:fb77f02, wu:fc52g10
Epitope
AA 1-260, full length
(29), (24), (16), (16), (13), (13), (12), (10), (7), (4), (3), (3), (3), (3), (2), (1), (1), (1), (1)
Reactivity
Human
(171), (72), (56), (10), (8), (8), (7), (6), (5), (4), (3), (2), (1), (1)
Host
Mouse
(127), (37), (15), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(7), (6), (5), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
ELISA, Western Blotting (WB)
(159), (78), (56), (43), (37), (22), (12), (11), (8), (5), (4), (3), (2), (1)
Pubmed 5 references available
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Quantity 50 μL
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Immunogen TARDBP (AAH01487.1, 1 a.a. ~ 260 a.a) full-length recombinant protein with GST tag.
Immunogen sequence: MSEYIRVTED ENDEPIEIPS EDDGTVLLST VTAQFPGACG LRYRNPVSQC MRGVRLVEGI LHAPDAGWGN LVYVVNYPKD NKRKMDETDA SSAVKVKRAV QKTSDLIVLG LPWKTTEQDL KEYFSTFGEV LMVQVKKDLK TGHSKGFGFV RFTEYETQVK VMSQRHMIDG RWCDCKLPNS KQSQDEPLRS RKVFVGRCTE DMTEDELREF FSQYGDVMDV FIPKPFRAFA FVTFADDQIA QSLCGEDLII KGISVHISNA
Cross-Reactivity Human
Alternative Name TARDBP (TARDBP Antibody Abstract)
Background Full Gene Name: TAR DNA binding protein
Synonyms: ALS10,TDP-43
Gene ID 23435
NCBI Accession NP_031401, NM_007375
Research Area Chromatin and Nuclear Signaling, Transcription Factors, DNA/RNA, Hormones, Cytokines
Application Notes Optimal working dilution should be determined by the investigator.
Comment

Product Quality tested by: Antibody Reactive Against Recombinant Protein.

Restrictions For Research Use only
Format Liquid
Buffer 50 % glycerol
Handling Advice Aliquot to avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store at -20 °C or lower. Aliquot to avoid repeated freezing and thawing.
Supplier Images
Western Blotting (WB) image for anti-TAR DNA Binding Protein (TARDBP) (AA 1-260), (full length) antibody (ABIN565079) TARDBP polyclonal antibody (A01), Lot # Abnova060510QCS1 Western Blot analysis of TAR...
Image no. 2 for anti-TAR DNA Binding Protein (TARDBP) (AA 1-260), (full length) antibody (ABIN565079) Western Blot detection against Immunogen (54.34 KDa) .
Product cited in: Ayala, Granado-Serrano, Cacabelos et al.: "Cell stress induces TDP-43 pathological changes associated with ERK1/2 dysfunction: implications in ALS." in: Acta neuropathologica, Vol. 122, Issue 3, pp. 259-70, 2011 (PubMed).

Schwab, Arai, Hasegawa et al.: "TDP-43 pathology in familial British dementia." in: Acta neuropathologica, Vol. 118, Issue 2, pp. 303-11, 2009 (PubMed).

Tatom, Wang, Dayton et al.: "Mimicking aspects of frontotemporal lobar degeneration and Lou Gehrig's disease in rats via TDP-43 overexpression." in: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 17, Issue 4, pp. 607-13, 2009 (PubMed).

Schwab, Arai, Hasegawa et al.: "Colocalization of transactivation-responsive DNA-binding protein 43 and huntingtin in inclusions of Huntington disease." in: Journal of neuropathology and experimental neurology, Vol. 67, Issue 12, pp. 1159-65, 2008 (PubMed).

Johnson, McCaffery, Lindquist et al.: "A yeast TDP-43 proteinopathy model: Exploring the molecular determinants of TDP-43 aggregation and cellular toxicity." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 17, pp. 6439-44, 2008 (PubMed).

Catalog No. ABIN565079
$298.57
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