You are viewing an incomplete version of our website. Please click to reload the website as full version.

TAR DNA Binding Protein (TARDBP) (AA 1-260), (full length) antibody

Details for Product No. ABIN565079, Supplier: Log in to see
Antigen
  • 1190002A23Rik
  • ALS10
  • C85084
  • DKFZp459I2127
  • TARDBP
  • tardbp
  • TDP-43
  • TDP43
  • Tdp43
  • wu:fb77f02
  • wu:fc52g10
Epitope
AA 1-260, full length
30
28
19
19
16
13
12
11
8
7
6
3
3
3
2
2
1
1
Reactivity
Human
230
109
80
28
23
23
20
19
12
8
6
4
2
1
Host
Mouse
128
92
16
1
Clonality
Polyclonal
Conjugate
Un-conjugated
10
10
8
6
5
5
5
5
5
4
4
4
3
3
3
3
3
3
3
3
1
1
1
1
1
1
1
Application
ELISA, Western Blotting (WB)
217
111
70
62
49
48
19
11
10
5
5
4
3
2
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

Immunogen TARDBP (AAH01487.1, 1 a.a. ~ 260 a.a) full-length recombinant protein with GST tag.
Immunogen sequence: MSEYIRVTED ENDEPIEIPS EDDGTVLLST VTAQFPGACG LRYRNPVSQC MRGVRLVEGI LHAPDAGWGN LVYVVNYPKD NKRKMDETDA SSAVKVKRAV QKTSDLIVLG LPWKTTEQDL KEYFSTFGEV LMVQVKKDLK TGHSKGFGFV RFTEYETQVK VMSQRHMIDG RWCDCKLPNS KQSQDEPLRS RKVFVGRCTE DMTEDELREF FSQYGDVMDV FIPKPFRAFA FVTFADDQIA QSLCGEDLII KGISVHISNA
Cross-Reactivity Human
Alternative Name TARDBP (TARDBP Antibody Abstract)
Background Full Gene Name: TAR DNA binding protein
Synonyms: ALS10,TDP-43
Gene ID 23435
NCBI Accession NP_031401, NM_007375
Research Area Chromatin and Nuclear Signaling, Transcription Factors, DNA/RNA, Hormones, Cytokines
Application Notes Optimal working dilution should be determined by the investigator.
Comment

Product Quality tested by: Antibody Reactive Against Recombinant Protein.

Restrictions For Research Use only
Format Liquid
Buffer 50 % glycerol
Handling Advice Aliquot to avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store at -20 °C or lower. Aliquot to avoid repeated freezing and thawing.
Supplier Images
Western Blotting (WB) image for anti-TAR DNA Binding Protein (TARDBP) (AA 1-260), (full length) antibody (ABIN565079) TARDBP polyclonal antibody (A01), Lot # Abnova060510QCS1 Western Blot analysis of TAR...
 image for anti-TAR DNA Binding Protein (TARDBP) (AA 1-260), (full length) antibody (ABIN565079) Western Blot detection against Immunogen (54.34 KDa) .
Product cited in: Ayala, Granado-Serrano, Cacabelos, Naudí, Ilieva, Boada, Caraballo-Miralles, Lladó, Ferrer, Pamplona, Portero-Otin: "Cell stress induces TDP-43 pathological changes associated with ERK1/2 dysfunction: implications in ALS." in: Acta neuropathologica, Vol. 122, Issue 3, pp. 259-70, 2011 (PubMed).

Tatom, Wang, Dayton, Skalli, Hutton, Dickson, Klein: "Mimicking aspects of frontotemporal lobar degeneration and Lou Gehrig's disease in rats via TDP-43 overexpression." in: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 17, Issue 4, pp. 607-13, 2009 (PubMed).

Schwab, Arai, Hasegawa, Akiyama, Yu, McGeer: "TDP-43 pathology in familial British dementia." in: Acta neuropathologica, Vol. 118, Issue 2, pp. 303-11, 2009 (PubMed).

Johnson, McCaffery, Lindquist, Gitler: "A yeast TDP-43 proteinopathy model: Exploring the molecular determinants of TDP-43 aggregation and cellular toxicity." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 17, pp. 6439-44, 2008 (PubMed).

Schwab, Arai, Hasegawa, Yu, McGeer: "Colocalization of transactivation-responsive DNA-binding protein 43 and huntingtin in inclusions of Huntington disease." in: Journal of neuropathology and experimental neurology, Vol. 67, Issue 12, pp. 1159-65, 2008 (PubMed).