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TAR DNA Binding Protein (TARDBP) (AA 1-260) antibody

Details for Product No. ABIN565079
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Antigen
Synonyms TARDBP, TDP43, DKFZp459I2127, tardbp, ALS10, TDP-43, 1190002A23Rik, C85084, Tdp43, wu:fb77f02, wu:fc52g10
Epitope
AA 1-260
(22), (21), (13), (12), (7), (7), (7), (4), (3), (2), (2), (1), (1), (1), (1), (1)
Reactivity
Human
(119), (59), (50), (23), (16), (8), (7), (6), (5), (3), (1), (1)
Host
Mouse
(92), (28), (5), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), ELISA
(108), (48), (30), (24), (24), (23), (10), (6), (2), (2), (1), (1)
Pubmed 5 references available
Quantity 50 µL
Shipping to United States (Change)
Availability Will be delivered in 11 to 12 Business Days
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Catalog No. ABIN565079
257.40 $
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Immunogen TARDBP (AAH01487.1, 1 a.a. ~ 260 a.a) full-length recombinant protein with GST tag.
Immunogen sequence: MSEYIRVTEDENDEPIEIPS EDDGTVLLSTVTAQFPGACG LRYRNPVSQCMRGVRLVEGI LHAPDAGWGNLVYVVNYPKD NKRKMDETDASSAVKVKRAV QKTSDLIVLGLPWKTTEQDL KEYFSTFGEVLMVQVKKDLK TGHSKGFGFVRFTEYETQVK VMSQRHMIDGRWCDCKLPNS KQSQDEPLRSRKVFVGRCTE DMTEDELREFFSQYGDVMDV FIPKPFRAFAFVTFADDQIA QSLCGEDLIIKGISVHISNA
Characteristics Mouse polyclonal antibody raised against a full-length recombinant TARDBP.
Alternative Name TARDBP
Background Gene: TAR DNA binding protein
Synonyms: ALS10, TDP-43
Gene ID 23435, BC001487
Research Area Chromatin and Nuclear Signaling, Transcription Factors, DNA/RNA, Hormones, Cytokines
Application Notes Application specialization: Cell lysate, Recombinant protein
Restrictions For Research Use only
Format Liquid
Buffer 50 % glycerol
Storage -20 °C
Storage Comment Store at -20 °C or lower. Aliquot to avoid repeated freezing and thawing.
Supplier Images
anti-TAR DNA Binding Protein (TARDBP) (AA 1-260) antibody TARDBP polyclonal antibody (A01), Lot # Abnova060510QCS1 Western Blot analysis of TARDBP expression in IMR-32 (ABIN1339499).
anti-TAR DNA Binding Protein (TARDBP) (AA 1-260) antibody (2) Western Blot detection against Immunogen (54.34 KDa) .
Product cited in: Johnson, McCaffery, Lindquist et al.: "A yeast TDP-43 proteinopathy model: Exploring the molecular determinants of TDP-43 aggregation and cellular toxicity." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 17, pp. 6439-44, 2008 (PubMed).

Schwab, Arai, Hasegawa et al.: "Colocalization of transactivation-responsive DNA-binding protein 43 and huntingtin in inclusions of Huntington disease." in: Journal of neuropathology and experimental neurology, Vol. 67, Issue 12, pp. 1159-65, 2008 (PubMed).

Tatom, Wang, Dayton et al.: "Mimicking aspects of frontotemporal lobar degeneration and Lou Gehrig's disease in rats via TDP-43 overexpression." in: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 17, Issue 4, pp. 607-13, 2009 (PubMed).

Schwab, Arai, Hasegawa et al.: "TDP-43 pathology in familial British dementia." in: Acta neuropathologica, Vol. 118, Issue 2, pp. 303-11, 2009 (PubMed).

Ayala, Granado-Serrano, Cacabelos et al.: "Cell stress induces TDP-43 pathological changes associated with ERK1/2 dysfunction: implications in ALS." in: Acta neuropathologica, Vol. 122, Issue 3, pp. 259-70, 2011 (PubMed).

Validation Images
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