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PHGDH antibody (AA 1-533)

PHGDH Reactivity: Human WB, ELISA, IHC (p), IF, IP Host: Mouse Monoclonal 4A3-1D6 unconjugated
Catalog No. ABIN565240
  • Target See all PHGDH Antibodies
    PHGDH (phosphoglycerate Dehydrogenase (PHGDH))
    Binding Specificity
    • 15
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-533
    Reactivity
    • 58
    • 15
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 53
    • 5
    • 1
    Mouse
    Clonality
    • 55
    • 4
    Monoclonal
    Conjugate
    • 26
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This PHGDH antibody is un-conjugated
    Application
    • 49
    • 22
    • 18
    • 13
    • 13
    • 12
    • 10
    • 7
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunoprecipitation (IP)
    Purpose
    Mouse monoclonal antibody raised against a full length recombinant PHGDH.
    Sequence
    MAFANLRKVL ISDSLDPCCR KILQDGGLQV VEKQNLSKEE LIAELQDCEG LIVRSATKVT ADVINAAEKL QVVGRAGTGV DNVDLEAATR KGILVMNTPN GNSLSAAELT CGMIMCLARQ IPQATASMKD GKWERKKFMG TELNGKTLGI LGLGRIGREV ATRMQSFGMK TIGYDPIISP EVSASFGVQQ LPLEEIWPLC DFITVHTPLL PSTTGLLNDN TFAQCKKGVR VVNCARGGIV DEGALLRALQ SGQCAGAALD VFTEEPPRDR ALVDHENVIS CPHLGASTKE AQSRCGEEIA VQFVDMVKGK SLTGVVNAQA LTSAFSPHTK PWIGLAEALG TLMRAWAGSP KGTIQVITQG TSLKNAGNCL SPAVIVGLLK EASKQADVNL VNAKLLVKEA GLNVTTSHSP AAPGEQGFGE CLLAVALAGA PYQAVGLVQG TTPVLQGLNG AVFRPEVPLR RDLPLLLFRT QTSDPAMLPT MIGLLAEAGV RLLSYQTSLV SDGETWHVMG ISSLLPSLEA WKQHVTEAFQ FHF
    Cross-Reactivity
    Human
    Characteristics
    Antibody Reactive Against Recombinant Protein.
    Immunogen
    PHGDH (AAH11262.1, 1 a.a. ~ 533 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    Clone
    4A3-1D6
    Isotype
    IgG1
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    In 1x PBS, pH 7.4
    Handling Advice
    Aliquot to avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Pollari, Käkönen, Edgren, Wolf, Kohonen, Sara, Guise, Nees, Kallioniemi: "Enhanced serine production by bone metastatic breast cancer cells stimulates osteoclastogenesis." in: Breast cancer research and treatment, Vol. 125, Issue 2, pp. 421-30, (2010) (PubMed).

  • Target
    PHGDH (phosphoglycerate Dehydrogenase (PHGDH))
    Alternative Name
    PHGDH (PHGDH Products)
    Background
    Full Gene Name: phosphoglycerate dehydrogenase
    Synonyms: 3-PGDH,3PGDH,MGC3017,PDG,PGAD,PGD,PGDH,SERA
    Gene ID
    26227
    Pathways
    Metabolism of Steroid Hormones and Vitamin D, Warburg Effect
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