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PHGDH antibody (AA 1-533)
PHGDH
Reactivity: Human
WB, ELISA, IHC (p), IF, IP
Host: Mouse
Monoclonal
4A3-1D6
unconjugated
Product Details anti-PHGDH Antibody
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Target
See all PHGDH Antibodies
PHGDH
(phosphoglycerate Dehydrogenase (PHGDH))
Binding Specificity
All epitopes for PHGDH antibodies
AA 1-533
Reactivity
All reactivities for PHGDH antibodies
Human
Host
All hosts for PHGDH antibodies
Mouse
Clonality
All clonalities for PHGDH antibodies
Monoclonal
Conjugate
All conjugates for PHGDH antibodies
This PHGDH antibody is un-conjugated
Application
All applications for PHGDH antibodies
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunoprecipitation (IP)
Purpose
Mouse monoclonal antibody raised against a full length recombinant PHGDH.
Sequence
MAFANLRKVL ISDSLDPCCR KILQDGGLQV VEKQNLSKEE LIAELQDCEG LIVRSATKVT ADVINAAEKL QVVGRAGTGV DNVDLEAATR KGILVMNTPN GNSLSAAELT CGMIMCLARQ IPQATASMKD GKWERKKFMG TELNGKTLGI LGLGRIGREV ATRMQSFGMK TIGYDPIISP EVSASFGVQQ LPLEEIWPLC DFITVHTPLL PSTTGLLNDN TFAQCKKGVR VVNCARGGIV DEGALLRALQ SGQCAGAALD VFTEEPPRDR ALVDHENVIS CPHLGASTKE AQSRCGEEIA VQFVDMVKGK SLTGVVNAQA LTSAFSPHTK PWIGLAEALG TLMRAWAGSP KGTIQVITQG TSLKNAGNCL SPAVIVGLLK EASKQADVNL VNAKLLVKEA GLNVTTSHSP AAPGEQGFGE CLLAVALAGA PYQAVGLVQG TTPVLQGLNG AVFRPEVPLR RDLPLLLFRT QTSDPAMLPT MIGLLAEAGV RLLSYQTSLV SDGETWHVMG ISSLLPSLEA WKQHVTEAFQ FHF
Cross-Reactivity
Human
Characteristics
Antibody Reactive Against Recombinant Protein.
Immunogen
PHGDH (AAH11262.1, 1 a.a. ~ 533 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Clone
4A3-1D6
Isotype
IgG1
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Buffer
In 1x PBS, pH 7.4
Handling Advice
Aliquot to avoid repeated freezing and thawing.
Storage
-20 °C
Storage Comment
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
References for anti-PHGDH antibody (ABIN565240)
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Pollari, Käkönen, Edgren, Wolf, Kohonen, Sara, Guise, Nees, Kallioniemi : "Enhanced serine production by bone metastatic breast cancer cells stimulates osteoclastogenesis. " in: Breast cancer research and treatment , Vol. 125 , Issue 2 , pp. 421-30 , (2010 ) (PubMed ).
Target Details for PHGDH
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Target
PHGDH
(phosphoglycerate Dehydrogenase (PHGDH))
Alternative Name
PHGDH (PHGDH Products )
Background
Full Gene Name: phosphoglycerate dehydrogenase Synonyms: 3-PGDH,3PGDH,MGC3017,PDG,PGAD,PGD,PGDH,SERA
Gene ID
26227
Pathways
Metabolism of Steroid Hormones and Vitamin D , Warburg Effect
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