DNAJC10 antibody (AA 688-793)

Catalog No. ABIN565732

Product Details anti-DNAJC10 Antibody

Target: DNAJC10 (DnaJ (Hsp40) Homolog, Subfamily C, Member 10 (DNAJC10))

Binding Specificity: AA 688-793

Reactivity: Human

Host: Mouse

Clonality: Polyclonal

Conjugate: This DNAJC10 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: Mouse polyclonal antibody raised against a partial recombinant DNAJC10.

Sequence: KNHWVIDFYA PWCGPCQNFA PEFELLARMI KGKVKAGKVD CQAYAQTCQK AGIRAYPTVK FYFYERAKRN FQEEQINTRD AKAIAALISE KLETLRNQGK RNKDEL

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: DNAJC10 (NP_061854, 688 a.a. ~ 793 a.a) partial recombinant protein with GST tag.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 50 % glycerol

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-DNAJC10 antibody (ABIN565732)

Ushioda, Hoseki, Nagata: "Glycosylation-independent ERAD pathway serves as a backup system under ER stress." in: Molecular biology of the cell, Vol. 24, Issue 20, pp. 3155-63, (2013) (PubMed).

Ushioda, Hoseki, Araki, Jansen, Thomas, Nagata: "ERdj5 is required as a disulfide reductase for degradation of misfolded proteins in the ER." in: Science (New York, N.Y.), Vol. 321, Issue 5888, pp. 569-72, (2008) (PubMed).

Corazzari, Lovat, Armstrong, Fimia, Hill, Birch-Machin, Redfern, Piacentini: "Targeting homeostatic mechanisms of endoplasmic reticulum stress to increase susceptibility of cancer cells to fenretinide-induced apoptosis: the role of stress proteins ERdj5 and ERp57." in: British journal of cancer, Vol. 96, Issue 7, pp. 1062-71, (2007) (PubMed).

Target Details for DNAJC10

Target: DNAJC10 (DnaJ (Hsp40) Homolog, Subfamily C, Member 10 (DNAJC10))

Alternative Name: DNAJC10 (DNAJC10 Products)

Synonyms: ERdj5 antibody, JPDI antibody, MTHr antibody, PDIA19 antibody, 1200006L06Rik antibody, D2Ertd706e antibody, dnajc10 antibody, zgc:162218 antibody, DnaJ heat shock protein family (Hsp40) member C10 antibody, DnaJ (Hsp40) homolog, subfamily C, member 10 antibody, DNAJC10 antibody, Dnajc10 antibody, dnajc10 antibody

Background: Full Gene Name: DnaJ (Hsp40) homolog, subfamily C, member 10
Synonyms: DKFZp434J1813,ERdj5,JPDI,MGC104194

Gene ID: 54431

NCBI Accession: NM_018981

Pathways: Cell RedoxHomeostasis