PTBP2 antibody (AA 1-532)

Catalog No. ABIN566177

Product Details anti-PTBP2 Antibody

Target: PTBP2 (Polypyrimidine Tract Binding Protein 2 (PTBP2))

Binding Specificity: AA 1-532

Reactivity: Human

Host: Mouse

Clonality: Polyclonal

Conjugate: This PTBP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: Mouse polyclonal antibody raised against a full-length recombinant PTBP2.

Sequence: MDGIVTEVAV GVKRGSDELL SGSVLSSPNS NMSSMVVTAN GNDSKKFKGE DKMDGAPSRV LHIRKLPGEV TETEVIALGL PFGKVTNILM LKGKNQAFLE LATEEAAITM VNYYSAVTPH LRNQPIYIQY SNHKELKTDN TLNQRAQAVL QAVTAVQTAN TPLSGTTVSE SAVTPAQSPV LRIIIDNMYY PVTLDVLHQI FSKFGAVLKI ITFTKNNQFQ ALLQYGDPVN AQQAKLALDG QNIYNACCTL RIDFSKLVNL NVKYNNDKSR DYTRPDLPSG DGQPALDPAI AAAFAKETSL LAVPGALSPL AIPNAAAAAA AAAAGRVGMP GVSAGGNTVL LVSNLNEEMV TPQSLFTLFG VYGDVQRVKI LYNKKDSALI QMADGNQSQL AMNHLNGQKM YGKIIRVTLS KHQTVQLPRE GLDDQGLTKD FGNSPLHRFK KPGSKNFQNI FPPSATLHLS NIPPSVAEED LRTLFANTGG TVKAFKFFQR DHKMALLQMA TVEEAIQALI DLHNYNLGEN HHLRVSFSKS TI

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: PTBP2 (AAH16582, 1 a.a. ~ 532 a.a) full-length recombinant protein with GST tag.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 50 % glycerol

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-PTBP2 antibody (ABIN566177)

Shibasaki, Tokunaga, Sakamoto, Sagara, Noguchi, Sasaoka, Yoshida: "PTB deficiency causes the loss of adherens junctions in the dorsal telencephalon and leads to lethal hydrocephalus." in: Cerebral cortex (New York, N.Y. : 1991), Vol. 23, Issue 8, pp. 1824-35, (2013) (PubMed).

Xu, Hecht: "Polypyrimidine tract-binding protein 2 binds to selective, intronic messenger RNA and microRNA targets in the mouse testis." in: Biology of reproduction, Vol. 84, Issue 3, pp. 435-9, (2011) (PubMed).

Suckale, Wendling, Masjkur, Jäger, Münster, Anastassiadis, Stewart, Solimena: "PTBP1 is required for embryonic development before gastrulation." in: PLoS ONE, Vol. 6, Issue 2, pp. e16992, (2011) (PubMed).

Sasabe, Futai, Ishiura: "Polypyrimidine tract-binding protein 1 regulates the alternative splicing of dopamine receptor D2." in: Journal of neurochemistry, Vol. 116, Issue 1, pp. 76-81, (2010) (PubMed).

Resnick, Segall, G, Lupowitz, Zisapel: "Alternative splicing of neurexins: a role for neuronal polypyrimidine tract binding protein." in: Neuroscience letters, Vol. 439, Issue 3, pp. 235-40, (2008) (PubMed).

Rolland, Evrard, Guitton, Lavigne, Calvel, Couvet, Jégou, Pineau: "Two-dimensional fluorescence difference gel electrophoresis analysis of spermatogenesis in the rat." in: Journal of proteome research, Vol. 6, Issue 2, pp. 683-97, (2007) (PubMed).

Target Details for PTBP2

Target: PTBP2 (Polypyrimidine Tract Binding Protein 2 (PTBP2))

Alternative Name: PTBP2 (PTBP2 Products)

Background: Full Gene Name: polypyrimidine tract binding protein 2
Synonyms: FLJ34897,PTB,PTBLP,brPTB,nPTB,nPTB5,nPTB6,nPTB7,nPTB8

Gene ID: 58155

Pathways: Ribonucleoprotein Complex Subunit Organization, SARS-CoV-2 Protein Interactome